Interconnection of periodontal disease and comorbidities: Evidence, mechanisms, and implications

G Hajishengallis - Periodontology 2000, 2022 - Wiley Online Library
Periodontitis, a microbiome‐driven inflammatory disease of the tooth‐attachment apparatus,
is epidemiologically linked with other disorders, including cardio‐metabolic, cognitive …

[HTML][HTML] A review of deep learning in dentistry

C Huang, J Wang, S Wang, Y Zhang - Neurocomputing, 2023 - Elsevier
Oral diseases have a significant impact on human health, often going unnoticed in their
early stages. Deep learning, a promising field in artificial intelligence, has shown remarkable …

Periodontitis and metabolic diseases (diabetes and obesity): Tackling multimorbidity

C Marruganti, JE Suvan, F D'Aiuto - Periodontology 2000, 2023 - Wiley Online Library
Noncommunicable diseases (NCDs) are multifactorial, long‐term, chronic conditions that
represent a burden to health‐care systems worldwide as they can only be controlled rather …

Bacterial lipopolysaccharide-induced endothelial activation and dysfunction: a new predictive and therapeutic paradigm for sepsis

M Wang, J Feng, D Zhou, J Wang - European Journal of Medical Research, 2023 - Springer
Background Lipopolysaccharide, a highly potent endotoxin responsible for severe sepsis, is
the major constituent of the outer membrane of gram-negative bacteria. Endothelial cells …

The role of the oral microbiome in smoking-related cardiovascular risk: a review of the literature exploring mechanisms and pathways

KA Maki, SM Ganesan, B Meeks, N Farmer… - Journal of translational …, 2022 - Springer
Cardiovascular disease is a leading cause of morbidity and mortality. Oral health is
associated with smoking and cardiovascular outcomes, but there are gaps in knowledge of …

Antidiabetic plants for the treatment of type 2 diabetes mellitus and associated Bacterial infections

MA Tienda-Vázquez, EM Melchor-Martínez… - Processes, 2023 - mdpi.com
Type 2 diabetes mellitus (T2DM) is the metabolic disease with the highest morbidity rates
worldwide. The condition is characterized by hyperglycemia, insulin resistance …

Association between periodontitis and inflammatory comorbidities: The common role of innate immune cells, underlying mechanisms and therapeutic targets

Q Wu, W Zhang, Y Lu, H Li, Y Yang, F Geng… - International …, 2024 - Elsevier
Periodontitis, which is related to various systemic diseases, is a chronic inflammatory
disease caused by periodontal dysbiosis of the microbiota. Multiple factors can influence the …

Lactobacillus gasseri RW2014 Ameliorates Hyperlipidemia by Modulating Bile Acid Metabolism and Gut Microbiota Composition in Rats

X Li, Y Xiao, Y Huang, L Song, M Li, Z Ren - Nutrients, 2022 - mdpi.com
Hyperlipidemia is a leading risk of cardiovascular and cerebrovascular disease. Dietary
supplementation with probiotics has been suggested as an alternative intervention to lower …

The recovery of the microbial community after plaque removal depends on periodontal health status

X Li, C Yu, B Zhang, X Shan, W Mao, Z Zhang… - npj Biofilms and …, 2023 - nature.com
Plaque accumulation and microbial community changes are important causes of periodontal
disease. Cleaned plaque microorganisms will reattach to form biofilms, but the recovery and …

Periodontitis, dental procedures, and young-onset cryptogenic stroke

J Leskelä, J Putaala… - Journal of Dental …, 2024 - journals.sagepub.com
Periodontitis is associated with an increased risk of ischemic stroke, and the risk may be
particularly high among young people with unexplained stroke etiology. Thus, we …