Preventing the development of cardiovascular problems is a key objective of
antihypertensive drugs. Many of the non-pressure related coronary risk factors for …

Cilnidipine, a fourth-generation both L-and N-type calcium channel blocker (CCB) is safe
and effective in lowering blood-pressure without reflex tachycardia compared to other …

Abstract Cilnidipine (CND), an anti-hypertensive drug, possesses low oral bioavailability
due to its poor aqueous solubility, low dissolution rate, and high gut wall metabolism. In the …

It is generally accepted that hypertension doubles the risk of cardiovascular disease, of
which coronary heart disease is the most common and lethal. Hypertension is a …

To compare amlodipine with cilnidipine on antihypertensive efficacy and incidence of pedal
edema in hypertensive individuals. This was a three months prospective, observational …

Cilnidipine is a 1, 4-dihydropyridine derived L/N-type calcium channel dual blocker
possessing neuroprotective and analgesic effects which are related to its N-type calcium …

Although a blockade or lack of N-type Ca2+ channels has been reported to suppress
neuronal injury induced by ischemia–reperfusion in several animal models, information is …

Cilnidipine, a calcium channel blocker having neuroprotective action and BCS Class II drug,
hence formulating in Microemulsion will increase solubility, absorption and bioavailability …

Background: Ankle edema is a common adverse effect of amlodipine, an L-type calcium
channel blocker (CCB). Cilnidipine is a newer L/N-type CCB, approved for treatment of …

The in vivo antisympathetic property of a dual L/N-type Ca2+ channel blocker cilnidipine
compared with that of typical N-type Ca2+ channel blockers has never been clarified. We …