Vaginal progesterone, oral progesterone, 17‐OHPC, cerclage, and pessary for preventing preterm birth in at‐risk singleton pregnancies: an updated systematic review …

A Jarde, O Lutsiv, J Beyene… - BJOG: An International …, 2019 - Wiley Online Library
Background Recent progesterone trials call for an update of previous syntheses of
interventions to prevent preterm birth. Objectives To compare the relative effects of different …

Prenatal administration of progesterone for preventing preterm birth in women considered to be at risk of preterm birth

JM Dodd, L Jones, V Flenady… - Cochrane Database …, 2013 - cochranelibrary.com
Background Preterm birth is a major complication of pregnancy associated with perinatal
mortality and morbidity. Progesterone for the prevention of preterm labour has been …

Evaluating Progestogens for Preventing Preterm birth International Collaborative (EPPPIC): meta-analysis of individual participant data from randomised controlled …

LA Stewart, M Simmonds, L Duley, A Llewellyn… - The Lancet, 2021 - thelancet.com
Background Preterm birth is a global health priority. Using a progestogen during high-risk
pregnancy could reduce preterm birth and adverse neonatal outcomes. Methods We did a …

Preterm labor and birth management: recommendations from the European Association of Perinatal Medicine

GC Di Renzo, L Cabero Roura… - The Journal of …, 2017 - Taylor & Francis
GC Di Renzo a, L. Cabero Roura b, F. Facchinetti c, H. Helmer d, C. Hubinont e, B.
Jacobsson f, JS Jørgensen g, RF Lamont h, i, A. Mikhailov j, N. Papantoniou k, V. Radzinsky …

Vaginal progesterone is as effective as cervical cerclage to prevent preterm birth in women with a singleton gestation, previous spontaneous preterm birth, and a short …

A Conde-Agudelo, R Romero, E Da Fonseca… - American journal of …, 2018 - Elsevier
Background An indirect comparison meta-analysis published in 2013 reported that both
vaginal progesterone and cerclage are equally efficacious for preventing preterm birth and …

The mechanical role of the cervix in pregnancy

KM Myers, H Feltovich, E Mazza, J Vink, M Bajka… - Journal of …, 2015 - Elsevier
Appropriate mechanical function of the uterine cervix is critical for maintaining a pregnancy
to term so that the fetus can develop fully. At the end of pregnancy, however, the cervix must …

Progesterone in normal and pathological pregnancy

GC Di Renzo, I Giardina, G Clerici, E Brillo… - … Molecular Biology and …, 2016 - degruyter.com
Progesterone is an essential hormone in the process of reproduction. It is involved in the
menstrual cycle, implantation and is essential for pregnancy maintenance. It has been …

Vaginal progesterone vs cervical cerclage for the prevention of preterm birth in women with a sonographic short cervix, previous preterm birth, and singleton gestation …

A Conde-Agudelo, R Romero, K Nicolaides… - American journal of …, 2013 - Elsevier
OBJECTIVE: No randomized controlled trial has compared vaginal progesterone and
cervical cerclage directly for the prevention of preterm birth in women with a sonographic …

Prevention of preterm parturition

JD Iams - New England Journal of Medicine, 2014 - Mass Medical Soc
Key Clinical Points Prevention of Preterm Parturition Despite advances in neonatal care,
preterm birth remains a leading cause of infant death in the United States, especially among …

Progesterone to prevent spontaneous preterm birth

R Romero, L Yeo, P Chaemsaithong… - Seminars in Fetal and …, 2014 - Elsevier
Preterm birth is the leading cause of perinatal morbidity and mortality worldwide, and its
prevention is an important healthcare priority. Preterm parturition is one of the 'great …