New insights into the pathogenesis and nonsurgical management of Graves orbitopathy
Graves orbitopathy, also known as thyroid eye disease or thyroid-associated orbitopathy, is
visually disabling, cosmetically disfiguring and has a substantial negative impact on a …
visually disabling, cosmetically disfiguring and has a substantial negative impact on a …
Prevalence of thyroid eye disease in Graves' disease: a meta‐analysis and systematic review
YH Chin, CH Ng, MH Lee, JWH Koh… - Clinical …, 2020 - Wiley Online Library
Objective Thyroid eye disease (TED) is a debilitating condition that frequently manifests in
patients suffering from Graves' disease (GD). This study aims to analyse the prevalence of …
patients suffering from Graves' disease (GD). This study aims to analyse the prevalence of …
Teprotumumab for patients with active thyroid eye disease: a pooled data analysis, subgroup analyses, and off-treatment follow-up results from two randomised …
GJ Kahaly, RS Douglas, RJ Holt, S Sile… - The Lancet Diabetes & …, 2021 - thelancet.com
Background Thyroid eye disease manifests inflammation and treatment-resistant proptosis
and diplopia. Teprotumumab, an insulin-like growth factor-1 receptor inhibiting monoclonal …
and diplopia. Teprotumumab, an insulin-like growth factor-1 receptor inhibiting monoclonal …
[HTML][HTML] Thyroid-associated ophthalmopathy
E Şahlı, K Gündüz - Turkish journal of ophthalmology, 2017 - ncbi.nlm.nih.gov
Thyroid-associated ophthalmopathy is the most frequent extrathyroidal involvement of
Graves' disease but it sometimes occurs in euthyroid or hypothyroid patients. Thyroid …
Graves' disease but it sometimes occurs in euthyroid or hypothyroid patients. Thyroid …
Thyroid eye disease: a review
DL Weiler - Clinical and experimental optometry, 2017 - Taylor & Francis
Thyroid eye disease is a multifactorial autoimmune disease with a spectrum of signs and
symptoms. Oftentimes, the diagnosis of thyroid eye disease is straightforward, based upon …
symptoms. Oftentimes, the diagnosis of thyroid eye disease is straightforward, based upon …
[HTML][HTML] Anti-IL-6 receptor tocilizumab in refractory Graves' orbitopathy: national multicenter observational study of 48 patients
L Sánchez-Bilbao, D Martínez-López… - Journal of Clinical …, 2020 - mdpi.com
Graves' orbitopathy (GO) is the most common extrathyroidal manifestation of Graves'
disease (GD). Our aim was to assess the efficacy and safety of Tocilizumab (TCZ) in GO …
disease (GD). Our aim was to assess the efficacy and safety of Tocilizumab (TCZ) in GO …
[HTML][HTML] Thyroid hormones and minerals in immunocorrection of disorders in autoimmune thyroid diseases
V Kravchenko, T Zakharchenko - Frontiers in Endocrinology, 2023 - frontiersin.org
Thyroid hormones and essential elements iodine (I), selenium (Se), iron (Fe), copper (Cu),
zinc (Zn), calcium (Ca), magnesium (Mg), etc. play an important role in the work of many …
zinc (Zn), calcium (Ca), magnesium (Mg), etc. play an important role in the work of many …
[HTML][HTML] Teprotumumab: interpreting the clinical trials in the context of thyroid eye disease pathogenesis and current therapies
BJ Winn, RC Kersten - Ophthalmology, 2021 - Elsevier
Teprotumumab, a monoclonal antibody targeted against the insulin-like growth factor 1 (IGF-
1) receptor, was recently approved by the United States Food and Drug Administration for …
1) receptor, was recently approved by the United States Food and Drug Administration for …
Current and emerging treatment strategies for Graves' orbitopathy
N Genere, MN Stan - Drugs, 2019 - Springer
Graves' orbitopathy is a debilitating disorder which occurs in patients with autoimmune
thyroid disease, mainly Graves' disease, and adds layers of complexity to management of …
thyroid disease, mainly Graves' disease, and adds layers of complexity to management of …
[HTML][HTML] A new era in the treatment of thyroid eye disease
A Patel, H Yang, RS Douglas - American journal of ophthalmology, 2019 - Elsevier
Purpose Improved understanding of thyroid eye disease (TED) pathogenesis has facilitated
identification of a targeted molecular approach for TED treatment offering the potential to halt …
identification of a targeted molecular approach for TED treatment offering the potential to halt …