[HTML][HTML] Platinum-based drugs for cancer therapy and anti-tumor strategies
C Zhang, C Xu, X Gao, Q Yao - Theranostics, 2022 - ncbi.nlm.nih.gov
Platinum-based drugs cisplatin, carboplatin, and oxaliplatin are widely used for
chemotherapeutic eradication of cancer. However, the side effects of platinum drugs, such …
chemotherapeutic eradication of cancer. However, the side effects of platinum drugs, such …
[HTML][HTML] Cancer chemotherapy and beyond: Current status, drug candidates, associated risks and progress in targeted therapeutics
U Anand, A Dey, AKS Chandel, R Sanyal, A Mishra… - Genes & …, 2023 - Elsevier
Cancer is an abnormal state of cells where they undergo uncontrolled proliferation and
produce aggressive malignancies that causes millions of deaths every year. With the new …
produce aggressive malignancies that causes millions of deaths every year. With the new …
Metallodrugs in cancer nanomedicine
Metal complexes are extensively used for cancer therapy. The multiple variables available
for tuning (metal, ligand, and metal–ligand interaction) offer unique opportunities for drug …
for tuning (metal, ligand, and metal–ligand interaction) offer unique opportunities for drug …
Cisplatin: The first metal based anticancer drug
S Ghosh - Bioorganic chemistry, 2019 - Elsevier
Abstract Cisplatin or (SP-4-2)-diamminedichloridoplatinum (II) is one of the most potential
and widely used drugs for the treatment of various solid cancers such as testicular, ovarian …
and widely used drugs for the treatment of various solid cancers such as testicular, ovarian …
Glutathione transferases: substrates, inihibitors and pro-drugs in cancer and neurodegenerative diseases
Glutathione transferase classical GSH conjugation activity plays a critical role in cellular
detoxification against xenobiotics and noxious compounds as well as against oxidative …
detoxification against xenobiotics and noxious compounds as well as against oxidative …
Organic cation transporters in health and disease
H Koepsell - Pharmacological reviews, 2020 - ASPET
The organic cation transporters (OCTs) OCT1, OCT2, OCT3, novel OCT (OCTN) 1, OCTN2,
multidrug and toxin exclusion (MATE) 1, and MATE kidney-specific 2 are polyspecific …
multidrug and toxin exclusion (MATE) 1, and MATE kidney-specific 2 are polyspecific …
Bioactivity and development of small non-platinum metal-based chemotherapeutics
Countless expectations converge in the multidisciplinary endeavour for the search and
development of effective and safe drugs in fighting cancer. Although they still embody a …
development of effective and safe drugs in fighting cancer. Although they still embody a …
Comprehensive review on how platinum-and taxane-based chemotherapy of ovarian cancer affects biology of normal cells
J Mikuła-Pietrasik, A Witucka, M Pakuła… - Cellular and Molecular …, 2019 - Springer
One of the most neglected aspects of chemotherapy are changes, and possible
consequences of these changes, that occur in normal somatic cells. In this review, we …
consequences of these changes, that occur in normal somatic cells. In this review, we …
[HTML][HTML] Chemotherapeutic agents for the treatment of metastatic breast cancer: An update
Breast cancer is the second greatest cause of death among women worldwide; it comprises
a group of heterogeneous diseases that evolves due to uncontrolled cellular growth and …
a group of heterogeneous diseases that evolves due to uncontrolled cellular growth and …
Long non-coding RNAs as a determinant of cancer drug resistance: Towards the overcoming of chemoresistance via modulation of lncRNAs
W Jiang, J Xia, S Xie, R Zou, S Pan, Z Wang… - Drug Resistance …, 2020 - Elsevier
Chemoresistance including intrinsic and acquired anticancer drug resistance continues to
be a primary hindrance towards curative cancer treatment. Therefore, deciphering the …
be a primary hindrance towards curative cancer treatment. Therefore, deciphering the …