Advances in hyaluronic acid for biomedical applications
A Yasin, Y Ren, J Li, Y Sheng, C Cao… - … in Bioengineering and …, 2022 - frontiersin.org
Hyaluronic acid (HA) is a large non-sulfated glycosaminoglycan that is the main component
of the extracellular matrix (ECM). Because of its strong and diversified functions applied in …
of the extracellular matrix (ECM). Because of its strong and diversified functions applied in …
Small-molecule drugs in immunotherapy
X Hao, Z Chen, H Li, M Wei, Z Zuo… - Mini Reviews in …, 2023 - ingentaconnect.com
Immunotherapy has been increasingly used in the treatment of cancer. Compared with
chemotherapy, immunotherapy relies on the autoimmune system with fewer side effects …
chemotherapy, immunotherapy relies on the autoimmune system with fewer side effects …
The application of tissue-engineered fish swim bladder vascular graft
H Bai, P Sun, H Wu, S Wei, B Xie, W Wang… - Communications …, 2021 - nature.com
Abstract Small diameter (< 6 mm) prosthetic vascular grafts continue to show very low long-
term patency, but bioengineered vascular grafts show promising results in preclinical …
term patency, but bioengineered vascular grafts show promising results in preclinical …
[HTML][HTML] A three-layered hydrogel patch with hierarchy releasing of PLGA nanoparticle drugs decrease neointimal hyperplasia
Hydrogel is a nature scaffold that can degraded in animal body and can be used as a drug
delivery system, we hypothesized that patch made of three layers of hydrogel with different …
delivery system, we hypothesized that patch made of three layers of hydrogel with different …
Hollow Cu2MoS4 nanoparticles loaded with immune checkpoint inhibitors reshape the tumor microenvironment to enhance immunotherapy for pancreatic cancer
Z Yao, C Qi, F Zhang, H Yao, C Wang, X Cao, C Zhao… - Acta Biomaterialia, 2024 - Elsevier
Pancreatic ductal adenocarcinoma (PDAC) is a fatal disease that responds poorly to single-
drug immunotherapy with PD-L1 (CD274) inhibitors. Here, we prepared mesoporous …
drug immunotherapy with PD-L1 (CD274) inhibitors. Here, we prepared mesoporous …
Application of the tissue-engineered plant scaffold as a vascular patch
Tissue-engineered plant scaffolds have shown promising applications in in vitro studies. To
assess the applicability of natural plant scaffolds as vascular patches, we tested …
assess the applicability of natural plant scaffolds as vascular patches, we tested …
[HTML][HTML] Integrin α9 regulates smooth muscle cell phenotype switching and vascular remodeling
Excessive proliferation of vascular smooth muscle cells (SMCs) remains a significant cause
of in-stent restenosis. Integrins, which are heterodimeric transmembrane receptors, play a …
of in-stent restenosis. Integrins, which are heterodimeric transmembrane receptors, play a …
[HTML][HTML] Immune checkpoint programmed death-1 mediates abdominal aortic aneurysm and pseudoaneurysm progression
P Sun, L Zhang, Y Gu, S Wei, Z Wang, M Li… - Biomedicine & …, 2021 - Elsevier
Purpose The causes and pathogenetic mechanisms underlying abdominal aortic aneurysms
(AAAs) and pseudoaneurysms are not fully understood. We hypothesized that inhibiting …
(AAAs) and pseudoaneurysms are not fully understood. We hypothesized that inhibiting …
A novel plant leaf patch absorbed with IL-33 antibody decreases venous neointimal hyperplasia
B Xie, X Bai, P Sun, L Zhang, S Wei… - Frontiers in Bioengineering …, 2021 - frontiersin.org
Introduction: We recently showed that a decellularized leaf scaffold can be loaded with
polylactic-co-glycolic acid (PLGA)-based rapamycin nanoparticles, this leaf patch can then …
polylactic-co-glycolic acid (PLGA)-based rapamycin nanoparticles, this leaf patch can then …
[HTML][HTML] A novel intramural TGF β 1 hydrogel delivery method to decrease murine abdominal aortic aneurysm and rat aortic pseudoaneurysm formation and …
H Bai, P Sun, S Wei, B Xie, M Li, Y Xu, W Wang… - Biomedicine & …, 2021 - Elsevier
Objectives Aneurysms are generally the result of dilation of all 3 layers of the vessel wall,
and pseudoaneurysms are the result of localized extravasation of blood that is contained by …
and pseudoaneurysms are the result of localized extravasation of blood that is contained by …