Genetics of human neural tube defects
Neural tube defects (NTDs) are common, severe congenital malformations whose causation
involves multiple genes and environmental factors. Although more than 200 genes are …
involves multiple genes and environmental factors. Although more than 200 genes are …
Mouse mutants with neural tube closure defects and their role in understanding human neural tube defects
MJ Harris, DM Juriloff - Birth Defects Research Part A: Clinical …, 2007 - Wiley Online Library
BACKGROUND: The number of mouse mutants and strains with neural tube closure defects
(NTDs) now exceeds 190, including 155 involving known genes, 33 with unidentified genes …
(NTDs) now exceeds 190, including 155 involving known genes, 33 with unidentified genes …
Genetic basis of neural tube defects
AG Bassuk, Z Kibar - Seminars in pediatric neurology, 2009 - Elsevier
Neural tube defects (NTDs) represent a common group of severe congenital malformations
of the central nervous system. They result from failure of neural tube closure during early …
of the central nervous system. They result from failure of neural tube closure during early …
Toward understanding the genetic basis of neural tube defects
Z Kibar, V Capra, P Gros - Clinical genetics, 2007 - Wiley Online Library
Neural tube defects (NTDs) represent a common group of severe congenital malformations
that result from failure of neural tube closure during early development. Their etiology is …
that result from failure of neural tube closure during early development. Their etiology is …
Maternal fumonisin exposure as a risk factor for neural tube defects
J Gelineau‐van Waes, KA Voss, VL Stevens… - Advances in food and …, 2009 - Elsevier
Fumonisins are mycotoxins produced by the fungus F. verticillioides, a common contaminant
of maize (corn) worldwide. Maternal consumption of fumonisin B 1‐contaminated maize …
of maize (corn) worldwide. Maternal consumption of fumonisin B 1‐contaminated maize …
[HTML][HTML] Classification, clinical features, and genetics of neural tube defects
MA Salih, WR Murshid, MZ Seidahmed - Saudi medical journal, 2014 - ncbi.nlm.nih.gov
Neural tube defects (NTDs) constitute a major health burden (0.5-2/1000 pregnancies
worldwide), and remain a preventable cause of still birth, neonatal, and infant death, or …
worldwide), and remain a preventable cause of still birth, neonatal, and infant death, or …
Closing in on mechanisms of open neural tube defects
S Lee, JG Gleeson - Trends in neurosciences, 2020 - cell.com
Neural tube defects (NTDs) represent a failure of the neural plate to complete the
developmental transition to a neural tube. NTDs are the most common birth anomaly of the …
developmental transition to a neural tube. NTDs are the most common birth anomaly of the …
[HTML][HTML] An FGF3-BMP signaling axis regulates caudal neural tube closure, neural crest specification and anterior-posterior axis extension
During vertebrate axis extension, adjacent tissue layers undergo profound morphological
changes: within the neuroepithelium, neural tube closure and neural crest formation are …
changes: within the neuroepithelium, neural tube closure and neural crest formation are …
Burden of Neural Tube Defects and Their Associated Factors in Africa: A Systematic Review and Meta‐Analysis
R Wakoya, M Afework - International Journal of Pediatrics, 2023 - Wiley Online Library
Background. Neural tube defects are a type of congenital anomaly caused by an
abnormality in the development of the brain and spinal cord during embryogenesis. They …
abnormality in the development of the brain and spinal cord during embryogenesis. They …
Whole exome sequencing identifies novel predisposing genes in neural tube defects
P Lemay, P De Marco, M Traverso… - Molecular genetics & …, 2019 - Wiley Online Library
Background Neural tube defects (NTD) are among the most common defects affecting 1:
1000 births. They are caused by a failure of neural tube closure during development. Their …
1000 births. They are caused by a failure of neural tube closure during development. Their …