We report a 7-year-old girl with spina bifida carrying a complex chromosome abnormality
resulting in duplication 16q12. 1–q22. 1. An abnormal karyotype was identified involving the …

Abstract Background Neural tube defects (NTDs) are common birth defects involving the
central nervous system. Recent studies on the etiology of human NTDs have raised the …

BACKGROUND: NTDs are considered complex disorders that arise from an interaction
between genetic and environmental factors. NTD family 8776 is a large multigenerational …

Clinical geneticists have contributed to the creation and operation of birth defects
surveillance systems and epidemiology research programs. Over the years, many continue …

BACKGROUND: Neural tube defects (NTDs) are considered complex, with both genetic and
environmental factors implicated. To date, no major causative genes have been identified in …

Background The term spina bifida refers to a group of neural tube defects that result in
malformations of the spinal cord and the surrounding vertebrae. Though the etiologies of …

Objective: Meningomyelocele (MMC) is a common central nervous system birth defect.
Various congenital and acquired abnormalities have been reported with MMC, some of …

Purpose Meningomyelocele is one of the most common and socioeconomically,
psychologically, and physically debilitating neurodevelopmental diseases. A few …

Multipoint linkage analysis in complex diseases requires the use of fast algorithms that can
handle many markers and a large number of moderately sized pedigrees with unknown …

神经管缺陷一级预防措施研究与实施现状-Current situation on primary prevention measures to
neural tube defects Chinese|English|Set Home|Join the collection Home Online Submission About …