Good microbes, bad genes? The dissemination of antimicrobial resistance in the human microbiome

A Crits-Christoph, HA Hallowell, K Koutouvalis… - Gut …, 2022 - Taylor & Francis
ABSTRACT A global rise in antimicrobial resistance among pathogenic bacteria has proved
to be a major public health threat, with the rate of multidrug-resistant bacterial infections …

The spread of antibiotic resistance genes in vivo model

S Tao, H Chen, N Li, T Wang… - Canadian Journal of …, 2022 - Wiley Online Library
Infections caused by antibiotic‐resistant bacteria are a major public health threat. The
emergence and spread of antibiotic resistance genes (ARGs) in the environment or clinical …

[HTML][HTML] Assessment of global health risk of antibiotic resistance genes

Z Zhang, Q Zhang, T Wang, N Xu, T Lu, W Hong… - Nature …, 2022 - nature.com
Antibiotic resistance genes (ARGs) have accelerated microbial threats to human health in
the last decade. Many genes can confer resistance, but evaluating the relative health risks of …

[HTML][HTML] Soil contamination in nearby natural areas mirrors that in urban greenspaces worldwide

YR Liu, MGA Van der Heijden, J Riedo… - nature …, 2023 - nature.com
Soil contamination is one of the main threats to ecosystem health and sustainability. Yet little
is known about the extent to which soil contaminants differ between urban greenspaces and …

[HTML][HTML] Strain-level characterization of broad host range mobile genetic elements transferring antibiotic resistance from the human microbiome

SC Forster, J Liu, N Kumar, EL Gulliver… - Nature …, 2022 - nature.com
Mobile genetic elements (MGEs) carrying antibiotic resistance genes (ARGs) disseminate
ARGs when they mobilise into new bacterial hosts. The nature of such horizontal gene …

mobileOG-db: a manually curated database of protein families mediating the life cycle of bacterial mobile genetic elements

CL Brown, J Mullet, F Hindi, JE Stoll… - Applied and …, 2022 - Am Soc Microbiol
Bacterial mobile genetic elements (MGEs) encode functional modules that perform both core
and accessory functions for the element, the latter of which are often only transiently …

Deciphering basic and key traits of antibiotic resistome in influent and effluent of hospital wastewater treatment systems

L Zhu, L Yuan, XY Shuai, ZJ Lin, YJ Sun, ZC Zhou… - Water Research, 2023 - Elsevier
Hospital wastewater treatment system (HWTS) is an important source and environmental
reservoir of clinically relevant antibiotic resistance genes (ARGs). However, how antibiotic …

[HTML][HTML] Antibiotic resistance in the commensal human gut microbiota

LE Lamberte, W van Schaik - Current Opinion in Microbiology, 2022 - Elsevier
Highlights•The human gut microbiota serves as a reservoir of antibiotic resistance
genes.•DNA sequencing and culture techniques are used to characterise the gut …

Antibiotic removal by microalgae-bacteria consortium: Metabolic pathways and microbial responses

I Eheneden, R Wang, J Zhao - Science of The Total Environment, 2023 - Elsevier
The proliferation of antibiotic-resistance genes is a result of the rise in the discharge of
residual antibiotics into waterbodies from a variety of sources. Antibiotic removal by …

[HTML][HTML] Population-level impacts of antibiotic usage on the human gut microbiome

K Lee, S Raguideau, K Sirén, F Asnicar… - Nature …, 2023 - nature.com
The widespread usage of antimicrobials has driven the evolution of resistance in pathogenic
microbes, both increased prevalence of antimicrobial resistance genes (ARGs) and their …