Technological advances and clinical research over the past few decades have given
radiation oncologists the capability to personalize treatments for accurate delivery of …

Radiation-induced second malignancies (RISM) is one of the important late side effects of
radiation therapy and has an impact on optimal treatment decision-making. Many factors …

Cellular exposure to ionizing radiation leads to oxidizing events that alter atomic structure
through direct interactions of radiation with target macromolecules or via products of water …

Purpose Automated delineation of structures and organs is a key step in medical imaging.
However, due to the large number and diversity of structures and the large variety of …

Radiotherapy has been driven by constant technological advances since the discovery of X-
rays in 1895. Radiotherapy aims to sculpt the optimal isodose on the tumour volume while …

Purpose: Commercial CT‐based image‐guided radiotherapy (IGRT) systems allow
widespread management of geometric variations in patient setup and internal organ motion …

Recent advances in radiotherapy have enabled the use of different types of particles, such
as protons and heavy ions, as well as refinements to the treatment of tumours with standard …

Background: The first UKCCCR Anal Cancer Trial (1996) demonstrated the benefit of
chemoradiation over radiotherapy (RT) alone for treating epidermoid anal cancer, and it …

Dose constraints are essential for performing dosimetry, especially for intensity modulation
and for radiotherapy under stereotaxic conditions. We present the update of the …

Background and purpose: Radiotherapy for breast cancer both decreases loco-regional
recurrence rates and improves overall survival. However, radiotherapy has also been …