Dieting is the most common approach to losing weight for the majority of obese and
overweight individuals. Restricting intake leads to weight loss in the short term, but, by itself …

The storage of triglyceride (TG) droplets in nonadipose tissues is called ectopic fat storage.
Ectopic fat is associated with insulin resistance and type 2 diabetes mellitus (T2DM). Not the …

Inefficient muscle long-chain fatty acid (LCFA) combustion is associated with insulin
resistance, but molecular links between mitochondrial fat catabolism and insulin action …

Insulin resistance progressing to type 2 diabetes mellitus (T2DM) is marked by a broad
perturbation of macronutrient intermediary metabolism. Understanding the biochemical …

The aim of this study was to examine the effect of aerobic exercise training on insulin
sensitivity in overweight and obese girls. Nineteen overweight and obese girls (mean±SD …

OBJECTIVE—The purpose of this article was to determine the relationships among total
body fat, visceral adipose tissue (VAT), fat cell size (FCS), ectopic fat deposition in liver …

Impaired mitochondrial function and structure and intramyocellular lipid (IMCL)
accumulation have been associated with obesity and Type 2 diabetes. We examined …

Lipids as fuel for energy provision originate from different sources: albumin-bound long-
chain fatty acids (LCFA) in the blood plasma, circulating very-low-density lipoproteins …

We previously reported an “athlete's paradox” in which endurance-trained athletes, who
possess a high oxidative capacity and enhanced insulin sensitivity, also have higher …

OBJECTIVE Age-associated insulin resistance may underlie the higher prevalence of type 2
diabetes in older adults. We examined a corollary hypothesis that obesity and level of …