Hippocampal cell loss and neurogenesis after fetal alcohol exposure: insights from different rodent models

J Gil-Mohapel, F Boehme, L Kainer, BR Christie - Brain research reviews, 2010 - Elsevier
Prenatal ethanol exposure is invariably detrimental to the developing central nervous
system and the hippocampus is particularly sensitive to the teratogenic effects of ethanol …

Does moderate drinking harm the fetal brain? Insights from animal models

CF Valenzuela, RA Morton, MR Diaz, L Topper - Trends in neurosciences, 2012 - cell.com
Although public health campaigns advise pregnant women to abstain from ethanol, drinking
during pregnancy is pervasive. Here, we highlight recent studies that have clearly …

Alcohol intoxications during adolescence increase motivation for alcohol in adult rats and induce neuroadaptations in the nucleus accumbens

S Alaux-Cantin, V Warnault, R Legastelois, B Botia… - …, 2013 - Elsevier
Adolescent alcohol binge drinking constitutes a major vulnerability factor to develop
alcoholism. However, mechanisms underlying this susceptibility remain unknown. We …

Prevalence, correlates, psychiatric comorbidities, and suicidality in a community population with problematic Internet use

BS Kim, SM Chang, JE Park, SJ Seong, SH Won… - Psychiatry …, 2016 - Elsevier
We examined the prevalence, correlates, and psychiatric comorbidities of community-
dwelling subjects with problematic Internet use (PIU). In an epidemiological survey of mental …

Effects of pre-natal alcohol exposure on hippocampal synaptic plasticity: Sex, age and methodological considerations

CJ Fontaine, AR Patten, HM Sickmann, JL Helfer… - Neuroscience & …, 2016 - Elsevier
The consumption of alcohol during gestation is detrimental to the developing central
nervous system (CNS). The severity of structural and functional brain alterations associated …

[HTML][HTML] Focus on: neurotransmitter systems

CF Valenzuela, MP Puglia, S Zucca - Alcohol Research & Health, 2011 - ncbi.nlm.nih.gov
Neurotransmitter systems have been long recognized as important targets of the
developmental actions of alcohol (ie, ethanol). Short-and long-term effects of ethanol on …

Genetic and epigenetic insights into fetal alcohol spectrum disorders

M Ramsay - Genome Medicine, 2010 - Springer
The magnitude of the detrimental effects following in utero alcohol exposure, including fetal
alcohol syndrome and other fetal alcohol spectrum disorders (FASD), is globally …

Voluntary exercise induces adult hippocampal neurogenesis and BDNF expression in a rodent model of fetal alcohol spectrum disorders

F Boehme, J Gil‐Mohapel, A Cox… - European Journal of …, 2011 - Wiley Online Library
Alcohol consumption during pregnancy can result in a myriad of health problems in the
affected offspring ranging from growth deficiencies to central nervous system impairments …

The dynamic nature of type 1 cannabinoid receptor (CB1) gene transcription

RB Laprairie, MEM Kelly… - British journal of …, 2012 - Wiley Online Library
The type 1 cannabinoid receptor (CB 1) is an integral component of the endocannabinoid
system that modulates several functions in the CNS and periphery. The majority of our …

DNA epigenetics in addiction susceptibility

G Kaplan, H Xu, K Abreu, J Feng - Frontiers in genetics, 2022 - frontiersin.org
Addiction is a chronically relapsing neuropsychiatric disease that occurs in some, but not all,
individuals who use substances of abuse. Relatively little is known about the mechanisms …