The definition 'resistance to antiplatelet drugs' should be limited to situations in which failure
of the drug to hit its pharmacological target has been documented by specific laboratory …

Aspirin is one of the cornerstones of treatment for cardiovascular disease. However, some
patients may be 'resistant'to its effect: this is associated with adverse cardiovascular …

Background—The inability of aspirin (acetylsalicylic acid [ASA]) to adequately suppress
platelet function is associated with future risk of myocardial infarction, stroke, and …

Individualised antiplatelet therapy and platelet function testing have attracted considerable
clinical interest, but several aspects of test performance have not been thoroughly …

Background Immune activation persists despite suppressive antiretroviral therapy (ART) in
human immunodeficiency virus (HIV) infection and predicts non-Acquired Immune …

Background Persistent systemic thromboxane generation, predominantly from nonplatelet
sources, in aspirin (ASA) users with cardiovascular disease (CVD) is a mortality risk factor …

It was the aim of the present study to perform a systematic review of the published studies
that estimated the prevalence of non-responders to aspirin, as assessed by the closure time …

The term 'resistance'to a drug should be used when a drug is unable to hit its
pharmacological target, due to inability to reach it (as a consequence of reduced …

Objective—Platelet endothelial aggregation receptor-1 (PEAR1) is a recently identified
platelet transmembrane protein that becomes activated by platelet contact. We looked for …

Insufficient platelet function suppression by aspirin is a predictor of cardiovascular events in
high‐risk patients. The authors assessed the impact of obesity on platelet responsiveness …