Skeletal muscle possesses a remarkable regenerative capacity that relies on the activity of
muscle stem cells, also known as satellite cells. The presence of non-myogenic cells also …

Neuromuscular disorders comprise a diverse group of human inborn diseases that arise
from defects in the structure and/or function of the muscle tissue—encompassing the muscle …

Exogenous glucocorticoids interact with the circadian clock, but little attention is paid to the
timing of intake. We recently found that intermittent once-weekly prednisone improved …

Glucocorticoid steroids are commonly prescribed for many inflammatory conditions, but
chronic daily use produces adverse effects, including muscle wasting and weakness. In …

Membrane repair is essential to cell survival. In skeletal muscle, injury often associates with
plasma membrane disruption. Additionally, muscular dystrophy is linked to mutations in …

Mutations of the DYSF gene leading to reduced dysferlin protein level causes limb girdle
muscular dystrophy type 2B (LGMD2B). Dysferlin facilitates sarcolemmal membrane repair …

Duchenne muscular dystrophy (DMD) is marked by pathogenic variants in the DMD gene,
leading to reduced or absent dystrophin translation, muscle fiber destruction, loss of …

Glucocorticoid steroids are widely used as immunomodulatory agents in acute and chronic
conditions. Glucocorticoid steroids such as prednisone and deflazacort are recommended …

Muscular dystrophies (MDs) are heterogeneous diseases, characterized by primary wasting
of skeletal muscle, which in severe cases, such as Duchenne Muscular Dystrophy (DMD) …

In humans, chronic glucocorticoid use is associated with side effects like muscle wasting,
obesity, and metabolic syndrome. Intermittent steroid dosing has been proposed in …