[HTML][HTML] Pharmacokinetic aspects of retinal drug delivery

EM Del Amo, AK Rimpelä, E Heikkinen, OK Kari… - Progress in retinal and …, 2017 - Elsevier
Drug delivery to the posterior eye segment is an important challenge in ophthalmology,
because many diseases affect the retina and choroid leading to impaired vision or …

TFOS Lifestyle: Impact of elective medications and procedures on the ocular surface

JAP Gomes, DT Azar, C Baudouin, E Bitton, W Chen… - The Ocular Surface, 2023 - Elsevier
The word “elective” refers to medications and procedures undertaken by choice or with a
lower grade of prioritization. Patients usually use elective medications or undergo elective …

[HTML][HTML] Stem cell-based retina models

K Achberger, JC Haderspeck, A Kleger… - Advanced Drug Delivery …, 2019 - Elsevier
From the early days of cell biological research, the eye—especially the retina—has evoked
broad interest among scientists. The retina has since been thoroughly investigated and …

A review of ocular complications associated with medications used for anxiety, depression, and stress

PA Constable, D Al-Dasooqi, R Bruce… - Clinical …, 2022 - Taylor & Francis
This review of commonly prescribed psychotropic drugs aims to update the clinician on
possible ophthalmic side effects that may include dry eye, diplopia, mydriasis, and cataracts …

Prediction of ocular drug distribution from systemic blood circulation

KS Vellonen, EM Soini, EM Del Amo… - Molecular …, 2016 - ACS Publications
Systemically circulating drugs may distribute to ocular tissues across the blood-ocular
barriers. Ocular distribution is utilized in the treatment of ocular diseases with systemic …

[HTML][HTML] A single drop in the eye–effects on the whole body?

A Vaajanen, H Vapaatalo - The open ophthalmology journal, 2017 - ncbi.nlm.nih.gov
A Single Drop in the Eye – Effects on the Whole Body? - PMC Back to Top Skip to main content
NIH NLM Logo Access keys NCBI Homepage MyNCBI Homepage Main Content Main …

Amiodarone-induced retinal neuronal cell apoptosis attenuated by IGF-1 via counter regulation of the PI3k/Akt/FoxO3a pathway

R Liao, F Yan, Z Zeng, M Farhan, P Little… - Molecular …, 2017 - Springer
Amiodarone (AM) is the most effective antiarrhythmic agent currently available. However,
clinical application of AM is limited by its serious toxic adverse effects including optic …

[HTML][HTML] New ophthalmic drug delivery systems

A Castro-Balado, C Mondelo-García, I Zarra-Ferro… - Farmacia …, 2020 - Elsevier
For decades, topical ophthalmic drug administration through the use of eye drops has been
the most widely used technique for the treatment of eye diseases. The development of …

Polimedicação em adultos e idosos cadastrados na Estratégia Saúde da Família: associação com fatores sociodemográficos, estilo de vida, rede de apoio social e …

N de Oliveira Andrade, AM Alves… - … de Medicina de …, 2020 - rbmfc.emnuvens.com.br
Introdução: Verifica-se, no contexto global, a modificação do perfil da morbimortalidade em
decorrência das transições demográfica e epidemiológica, relacionadas ao aumento do …

Advances in the pharmacogenomics of adverse drug reactions

SL Collins, DF Carr, M Pirmohamed - Drug safety, 2016 - Springer
Rapid developments in pharmacogenomics have been noticeable in recent years, and
much of this knowledge has improved understanding of adverse drug reactions. This …