Cancers in mouse and man express multiple tumor-specific as well as tumor-associated
antigens. Immunodominance in the host response to these antigens can result in successive …

Background: Infection with human papillomavirus (HPV) type 16 (HPV16) is a major cause
of high-grade cervical intraepithelial neoplasia (CIN). Experiments were planned to evaluate …

Certain human cancers are linked to infection by oncogenic viruses that are able to cause
transformation of the normal host cell into a cancerous cell. Human papillomavirus (HPV) …

Targeting exogenous antigen into the MHC class I‐restricted presentation pathway is a
prerequisite for the induction of cytotoxic T lymphocytes (CTL) which have been shown to …

Tat, the trans activation protein of HIV, is produced early upon infection to promote and
expand HIV replication and transmission. However, Tat appears to also have effects on …

Cervical cancer is the second leading cause of cancer in women worldwide. Human
papillomavirus (HPV) is responsible for all cases of cervical cancer. Commercial …

Dendritic cells (DCs) represent a unique junction from which to initiate antigen-specific
immunity. One of the most challenging obstacles for DC-based immunotherapy has been the …

A triple negative breast cancer model using the murine 4T1 tumor cell line was used to
explore the efficacy of an adjuvanted survivin peptide microparticle vaccine using tumor …

Carcinomas of the anogenital tract, particularly cancer of the cervix, account for almost 12%
of all cancers in women, and so represent the second most frequent gynecological …

Human papillomavirus (HPV)‐induced lesions are distinct in that they have targetable
foreign antigens, the expression of which is necessary to maintain the cancerous phenotype …