Detection of specific antibody-ligand interactions with a self-induced back-action actuated nanopore electrophoresis sensor

SSS Peri, MK Sabnani, MU Raza, S Ghaffari… - …, 2019 - iopscience.iop.org
Recent advances in plasmonic nanopore technologies have enabled the use of concurrently
acquired bimodal optical-electrical data for improved quantification of molecular interactions …

Chimeric virus-like particles of the human papillomavirus type 16 (HPV 16) as a prophylactic and therapeutic vaccine

I Jochmus, K Schäfer, S Faath, M Müller… - Archives of medical …, 1999 - Elsevier
Infection by certain human papillomaviruses (HPV), most notably HPV types 16 and 18, is
the major risk factor for cervical cancer. Worldwide, this disease represents the second most …

Development and Validation of a Fluorescence Polarization-Based Competitive Peptide-Binding Assay for HLA-A* 0201 A New Tool for Epitope Discovery

R Buchli, RS VanGundy, HD Hickman-Miller… - Biochemistry, 2005 - ACS Publications
Various approaches are currently proposed to successfully develop therapies for the
prevention and treatment of infectious diseases and cancer. One of the most promising …

Protective anti-tumor immunity induced by vaccination with recombinant adenoviruses encoding multiple tumor-associated cytotoxic T lymphocyte epitopes in a string …

REM Toes, RC Hoeben… - Proceedings of the …, 1997 - National Acad Sciences
Vaccines harboring genes that encode functional oncoproteins are intrinsically hazardous,
as their application may lead to introduction of these genes into normal cells and thereby to …

The B subunit of Shiga toxin coupled to full‐size antigenic protein elicits humoral and cell‐mediated immune responses associated with a Th1‐dominant polarization

N Haicheur, F Benchetrit, M Amessou… - International …, 2003 - academic.oup.com
A number of studies in animal models and humans have shown that both humoral andcell‐
mediated immune responses play an important role in the control of viral infection and tumor …

H1 histone and differentiation of dendritic cells. A molecular target for tumor-derived factors

DI Gabrilovich, P Cheng, Y Fan, B Yu… - Journal of leukocyte …, 2002 - academic.oup.com
Dendritic cells (DC) play a central role in antitumor immune responses. Abnormal
differentiation of DC and their inability to stimulate T cells are important factors in tumor …

Human T-cell responses to HLA-A-restricted high binding affinity peptides of human papillomavirus type 18 proteins E6 and E7

MP Rudolf, S Man, CJM Melief, A Sette, WM Kast - Clinical cancer research, 2001 - AACR
Abstract Human Papillomaviruses (HPVs) are sexually transmitted pathogens, which are
implicated in the etiology of cervical cancer. The early proteins E6 and E7 of HPV have …

[HTML][HTML] A therapeutic DNA vaccine targeting HPV16 E7 in combination with anti-PD-1/PD-L1 enhanced tumor regression and cytotoxic immune responses

X Han, Z Gao, Y Cheng, S Wu, J Chen… - International Journal of …, 2023 - mdpi.com
Persistent infection of high-risk human papillomavirus (HPV) and the expression of E6 and
E7 oncoproteins are the main causes of cervical cancer. Several prophylactic HPV vaccines …

Therapeutic vaccines for cervical cancer: dendritic cell-based immunotherapy

AD Santin, S Bellone, JJ Roman… - Current …, 2005 - ingentaconnect.com
Human papillomavirus (HPV) infection represents the most important risk factor for the
development of cervical dysplasia and cervical cancer. Several lines of evidence suggest …

Human papillomavirus type 16 E7 DNA vaccine: mutation in the open reading frame of E7 enhances specific cytotoxic T-lymphocyte induction and antitumor activity

W Shi, P Bu, J Liu, A Polack, S Fisher, L Qiao - Journal of virology, 1999 - Am Soc Microbiol
ABSTRACT A human papillomavirus type 16 E7 DNA vaccine with the open reading frame
encoding mutations in two zinc-binding motifs expressed a rapidly degraded E7 protein …