Simple Summary Childhood cancers are mostly of unknown etiology and represent
devastating diagnoses. The clinical benefits of steadily increasing tumor control and survival …

In humans, glioblastoma is the most prevalent primary malignant brain tumor. Usually,
glioblastoma has specific characteristics, such as aggressive cell proliferation and rapid …

PURPOSE Rhabdomyosarcoma is the most common soft tissue sarcoma of childhood.
Despite aggressive therapy, the 5-year survival rate for patients with metastatic or recurrent …

Paediatric rhabdomyosarcoma (RMS) is a soft tissue malignancy of mesenchymal origin that
is thought to arise as a consequence of derailed myogenic differentiation. Despite intensive …

Triggered drug delivery strategies have been shown to enhance drug accumulation at target
diseased sites in comparison to administration of free drug. In particular, many studies have …

Relapsed rhabdomyosarcoma (RMS) represents a significant therapeutic challenge. Nearly
one-third of patients diagnosed with localized RMS and over two-thirds of patients with …

Most children with tumors will require one or more surgical interventions as part of the care
and treatment, including making a diagnosis, obtaining adequate venous access …

Rhabdomyosarcoma, the most common soft tissue sarcoma noted in childhood, requires
multimodality treatment, including chemotherapy, surgical resection, and/or radiation …

In this study, it was aimed to exploit no chemical drug to treat cancer by starvation-
immunotherapy combination. We used PD-L1 siRNA to down-regulate checkpoint protein …

Rhabdomyosarcoma (RMS) is the most common soft tissue sarcoma in childhood. Recently,
we demonstrated the overexpression of both DNA methyltransferase 3A (DNMT3A) and 3B …