Childhood cancer: occurrence, treatment and risk of second primary malignancies
S Zahnreich, H Schmidberger - Cancers, 2021 - mdpi.com
Simple Summary Childhood cancers are mostly of unknown etiology and represent
devastating diagnoses. The clinical benefits of steadily increasing tumor control and survival …
devastating diagnoses. The clinical benefits of steadily increasing tumor control and survival …
Natural compounds as promising adjuvant agents in the treatment of gliomas
In humans, glioblastoma is the most prevalent primary malignant brain tumor. Usually,
glioblastoma has specific characteristics, such as aggressive cell proliferation and rapid …
glioblastoma has specific characteristics, such as aggressive cell proliferation and rapid …
Genomic classification and clinical outcome in rhabdomyosarcoma: a report from an international consortium
PURPOSE Rhabdomyosarcoma is the most common soft tissue sarcoma of childhood.
Despite aggressive therapy, the 5-year survival rate for patients with metastatic or recurrent …
Despite aggressive therapy, the 5-year survival rate for patients with metastatic or recurrent …
Single-cell transcriptomics reveals immune suppression and cell states predictive of patient outcomes in rhabdomyosarcoma
J DeMartino, MT Meister, LL Visser, M Brok… - Nature …, 2023 - nature.com
Paediatric rhabdomyosarcoma (RMS) is a soft tissue malignancy of mesenchymal origin that
is thought to arise as a consequence of derailed myogenic differentiation. Despite intensive …
is thought to arise as a consequence of derailed myogenic differentiation. Despite intensive …
Triggered release from thermosensitive liposomes improves tumor targeting of vinorelbine
M Regenold, K Kaneko, X Wang, HB Peng… - Journal of Controlled …, 2023 - Elsevier
Triggered drug delivery strategies have been shown to enhance drug accumulation at target
diseased sites in comparison to administration of free drug. In particular, many studies have …
diseased sites in comparison to administration of free drug. In particular, many studies have …
Relapsed rhabdomyosarcoma
CM Heske, L Mascarenhas - Journal of clinical medicine, 2021 - mdpi.com
Relapsed rhabdomyosarcoma (RMS) represents a significant therapeutic challenge. Nearly
one-third of patients diagnosed with localized RMS and over two-thirds of patients with …
one-third of patients diagnosed with localized RMS and over two-thirds of patients with …
[HTML][HTML] International society of paediatric surgical oncology (IPSO) surgical practice guidelines
SCV Abib, CH Chui, S Cox, AH Abdelhafeez… - …, 2022 - ncbi.nlm.nih.gov
Most children with tumors will require one or more surgical interventions as part of the care
and treatment, including making a diagnosis, obtaining adequate venous access …
and treatment, including making a diagnosis, obtaining adequate venous access …
Recent advances and challenges in the treatment of rhabdomyosarcoma
S Miwa, N Yamamoto, K Hayashi, A Takeuchi… - Cancers, 2020 - mdpi.com
Rhabdomyosarcoma, the most common soft tissue sarcoma noted in childhood, requires
multimodality treatment, including chemotherapy, surgical resection, and/or radiation …
multimodality treatment, including chemotherapy, surgical resection, and/or radiation …
[HTML][HTML] Enhanced drug release from a pH-responsive nanocarrier can augment colon cancer treatment by blocking PD-L1 checkpoint and consuming tumor glucose
K Guo, Y Liu, M Ding, Q Sun, QTH Shubhra - Materials & Design, 2022 - Elsevier
In this study, it was aimed to exploit no chemical drug to treat cancer by starvation-
immunotherapy combination. We used PD-L1 siRNA to down-regulate checkpoint protein …
immunotherapy combination. We used PD-L1 siRNA to down-regulate checkpoint protein …
DNMT3A and DNMT3B targeting as an effective radiosensitizing strategy in embryonal rhabdomyosarcoma
S Camero, G Vitali, P Pontecorvi, S Ceccarelli… - Cells, 2021 - mdpi.com
Rhabdomyosarcoma (RMS) is the most common soft tissue sarcoma in childhood. Recently,
we demonstrated the overexpression of both DNA methyltransferase 3A (DNMT3A) and 3B …
we demonstrated the overexpression of both DNA methyltransferase 3A (DNMT3A) and 3B …