Antimicrobial resistance and mechanisms of epigenetic regulation

X Wang, D Yu, L Chen - Frontiers in Cellular and Infection …, 2023 - frontiersin.org
The rampant use of antibiotics in animal husbandry, farming and clinical disease treatment
has led to a significant issue with pathogen resistance worldwide over the past decades …

Networks of resistance: Small RNA control of antibiotic resistance

DG Mediati, S Wu, W Wu, JJ Tree - Trends in Genetics, 2021 - cell.com
The golden age of antibiotics has passed, and the threat of untreatable antimicrobial
resistant infections is now a reality for many individuals. Understanding how bacteria resist …

Molecular mechanism of Hfq-dependent sRNA1039 and sRNA1600 regulating antibiotic resistance and virulence in Shigella sonnei

Y Du, Y Wang, J Geng, J Long, H Yang, G Duan… - International Journal of …, 2024 - Elsevier
Bacillary dysentery caused by Shigella spp. is a significant concern for human health. Small
non-coding RNA (sRNA) plays a crucial role in regulating antibiotic resistance and virulence …

Small RNAs as fundamental players in the transference of information during bacterial infectious diseases

JJ González Plaza - Frontiers in Molecular Biosciences, 2020 - frontiersin.org
Communication shapes life on Earth. Transference of information has played a paramount
role on the evolution of all living or extinct organisms since the appearance of life. Success …

Deciphering the genetic network and programmed regulation of antimicrobial resistance in bacterial pathogens

T Ramamurthy, A Ghosh, G Chowdhury… - Frontiers in Cellular …, 2022 - frontiersin.org
Antimicrobial resistance (AMR) in bacteria is an important global health problem affecting
humans, animals, and the environment. AMR is considered as one of the major components …

[HTML][HTML] Involvement of RNA chaperone hfq in the regulation of antibiotic resistance and virulence in Shigella sonnei

Y Wang, Y Teng, J Geng, J Long, H Yang, G Duan… - Research in …, 2023 - Elsevier
The host factor for RNA phage Qβ replicase (Hfq) is a crucial post-transcriptional regulator in
many bacterial pathogens, facilitating the interaction between small non-coding RNAs …

The Acinetobacter baumannii model can explain the role of small non-coding RNAs as potential mediators of host-pathogen interactions

M Sarshar, D Scribano, AT Palamara… - Frontiers in Molecular …, 2022 - frontiersin.org
Bacterial small RNAs (sRNAs) research has accelerated over the past decade, boosted by
advances in RNA-seq technologies and methodologies for capturing both protein–RNA and …

Adaptation of a fluoroquinolone-sensitive Shigella sonnei to norfloxacin exposure

BC Wong, SKK Law… - Royal Society …, 2024 - royalsocietypublishing.org
Shigella causes shigellosis that requires antibiotic treatment in severe cases. Sublethal
antibiotic concentrations can promote resistance, but their effect on antibiotic-sensitive …

The many facets of the small non-coding RNA RsaE (RoxS) in metabolic niche adaptation of Gram-positive bacteria

G Marincola, FDR Wencker, W Ziebuhr - Journal of molecular biology, 2019 - Elsevier
Small regulatory RNAs (sRNAs) are increasingly recognized as players in the complex
regulatory networks governing bacterial gene expression. RsaE (synonym RoxS) is an …

[HTML][HTML] 非编码小RNA 对细菌毒力及耐药性的调控作用研究进展

谢兆邦, 刘欢, 雷化雨, 史懿乐, 赵燕妮 - 微生物学通报, 2023 - actamicro.ijournals.cn
近年来的研究发现, 细菌非编码小RNA (small non-coding RNA, sRNA) 对其不同生理进程起
到了重要的调控作用. 随着大量sRNA 被发现并鉴定, 细菌sRNA 的功能被逐步阐明 …