Chronic stress has been extensively linked to disturbances in glutamatergic signalling.
Emerging from this field of research is a considerable number of studies identifying the …

Striatal medium-sized spiny neurons (MSNs) are highly vulnerable to ischemia. A brief
ischemic insult, produced by oxygen and glucose deprivation (OGD), can induce ischemic …

Objective: The adenosinergic system may influence excitability in the brain. Endogenous
and exogenous adenosine has anticonvulsant activity presumably by activating A1 …

Adenosine is a neuromodulator implicated in nervous system development and plasticity
and its effects are mediated by inhibitory (A1, A3) and excitatory (A2a, A2b) receptors. The …

Abstract Hippocampal somatostatin (SST)-neprilysin (NEP) system functions as a defense
system against neurotoxic soluble amyloid-β oligomers associated with onset of Alzheimer's …

Adenosine is an endogenous neuromodulator previously shown to suppress synaptic
transmission and membrane excitability in the CNS. In this study we have determined the …

Synaptic transmission is an essential process for neuron physiology. Such process is
enabled in part due to modulation of neurotransmitter release. Adenosine is a synaptic …

目的: 观察腺苷(Adenosine, Ado) 对缰核(Habenula nucleus, Hb) 神经元单位放电的影响及
外侧缰核内c—fos 蛋白表达的变化, 探讨腺苷对影响睡眠的缰核神经元活动及相关基因表达的 …

Adenosine is a homeostatic modulator in all cells, being produced from intracellular ATP as
a consequence of increased workload or noxious stimuli. Extracellular adenosine can then …

目的了解快速眼动睡眠剥夺改善抑郁情绪的可能机制. 方法将大鼠分为正常对照组(A 组),
抑郁模型组(B 组), 抑郁模型+ 72 h 睡眠剥夺组(C 组), 在建立慢性轻度不可预见性应激的抑郁 …