Metabolic dysfunction-associated steatohepatitis (MASH) is one of the major risk factors for
chronic liver disease and hepatocellular carcinoma (HCC). The incidence of MASH in …

Introduction Hepatocellular carcinoma (HCC) represents a significant burden globally, which
ranks sixth among the most frequently diagnosed cancers and stands as the third leading …

Nonalcoholic steatohepatitis (NASH) is the fastest growing cause of hepatocellular
carcinoma (HCC) in the United States. Changes in N-glycosylation on specific glycosites of …

Aberrant glycosylation has gained significant interest for biomarker discovery. However, low
detectability, complex glycan structures, and heterogeneity present challenges in …

Despite advances in understanding the development and progression of cancer in recent
years, there remains a lack of comprehensive characterization of the cancer glycoproteome …

Protein post-translational modification (PTM) is a covalent process that occurs in proteins
during or after translation through the addition or removal of one or more functional groups …

Background Hepatocellular carcinoma (HCC) is the most prevalent primary liver cancer with
one of the highest cancer‐related mortality rates worldwide. Early diagnosis is crucial for …

Introduction Glyphosate-based herbicides (GBHs) have been shown to have significant
neurotoxic effects, affecting both the structure and function of the brain, and potentially …

Background There is a need for new serum biomarkers for early detection of hepatocellular
carcinoma (HCC). Haptoglobin (Hp) N-glycosylation is altered in HCC, but the diagnostic …

Protein glycosylation is the co‐and/or post‐translational modification of proteins with
oligosaccharides (glycans). This process is not template based and can introduce a …