Is it time for immunopsychiatry in psychotic disorders?

M Leboyer, J Oliveira, R Tamouza, L Groc - Psychopharmacology, 2016 - Springer
Introduction: Immune dysregulation is suggested to play an important aetiological role in
schizophrenia (SZ) and bipolar disorder (BD) potentially driving neurodevelopmental …

DNA methylation and the evolution of developmental complexity in plants

K Bräutigam, Q Cronk - Frontiers in Plant Science, 2018 - frontiersin.org
All land plants so far examined use DNA methylation to silence transposons (TEs). DNA
methylation therefore appears to have been co-opted in evolution from an original function …

Understanding what determines the frequency and pattern of human germline mutations

N Arnheim, P Calabrese - Nature Reviews Genetics, 2009 - nature.com
Surprising findings about human germline mutation have come from applying new
technologies to detect rare mutations in germline DNA, from analysing DNA sequence …

In utero exposure to endocrine-disrupting chemicals, maternal factors and alterations in the epigenetic landscape underlying later-life health effects

C Lite, GL Raja, M Juliet, VV Sridhar… - Environmental …, 2022 - Elsevier
Widespread persistence of endocrine-disrupting chemicals (EDCs) in the environment has
mandated the need to study their potential effects on an individual's long-term health after …

Regulation and flexibility of genomic imprinting during seed development

MT Raissig, C Baroux, U Grossniklaus - The Plant Cell, 2011 - academic.oup.com
Genomic imprinting results in monoallelic gene expression in a parent-of-origin–dependent
manner. It is achieved by the differential epigenetic marking of parental alleles. Over the past …

Effects on specific promoter DNA methylation in zebrafish embryos and larvae following benzo [a] pyrene exposure

J Corrales, X Fang, C Thornton, W Mei… - … and Physiology Part C …, 2014 - Elsevier
Abstract Benzo [a] pyrene (BaP) is an established carcinogen and reproductive and
developmental toxicant. BaP exposure in humans and animals has been linked to infertility …

Expression profiling reveals developmentally regulated lncRNA repertoire in the mouse male germline

J Bao, J Wu, AS Schuster, GW Hennig… - Biology of …, 2013 - academic.oup.com
In mammals, the transcriptome of large noncoding RNAs (lncRNAs) is believed to be greater
than that of messenger RNAs (mRNAs). Some lncRNAs, especially large intergenic …

Maximizing the ovarian reserve in mice by evading LINE-1 genotoxicity

ME Tharp, S Malki, A Bortvin - Nature Communications, 2020 - nature.com
Female reproductive success critically depends on the size and quality of a finite ovarian
reserve. Paradoxically, mammals eliminate up to 80% of the initial oocyte pool through the …

Nature or nurture: let food be your epigenetic medicine in chronic inflammatory disorders

KS vel Szic, MN Ndlovu, G Haegeman… - Biochemical …, 2010 - Elsevier
Numerous clinical, physiopathological and epidemiological studies have underlined the
detrimental or beneficial role of nutritional factors in complex inflammation related disorders …

Environmental epigenetics and epigenetic inheritance in domestic farm animals

RP Thompson, E Nilsson, MK Skinner - Animal Reproduction Science, 2020 - Elsevier
Epigenetics refers to molecular factors and processes around DNA that can affect genome
activity and gene expression independent of DNA sequence. Epigenetic mechanisms drive …