Magnetic resonance imaging (MRI) has become an important tool for the clinical evaluation
of patients with cardiovascular disease. Since its introduction in the late 1980s, 2 …

Valvular heart diseases (VHD) are a major health burden, affecting millions of people
worldwide. The treatments for such diseases rely on medicine, valve repair, and artificial …

The biomechanical factors that result from the haemodynamic load on the cardiovascular
system are a common denominator of several vascular pathologies. Thickening and …

The valves of the heart are crucial for ensuring that blood flows in one direction from the
heart, through the lungs and back to the rest of the body. Heart valve development is …

Introduction: Heart valve disease is an increasingly prevalent and clinically serious
condition. There are no clinically effective biological diagnostics or treatment strategies. The …

Flow through the AV is pulsatile in nature and directly depends on multiple factors, including
LV systolic and diastolic function, aortic pressure and compliance, leaflet mobility, and LV …

Calcific aortic valve disease (CAVD) is associated with increased morbidity and mortality.
We aimed to elucidate the 30-year epidemiology of CAVD globally. Global CAVD incidence …

Aortic stenosis (AS) is an acute and chronic cardiovascular disease and If left untreated,
50% of these patients will die within two years of developing symptoms. AS is characterized …

Calcific aortic valve disease (CAVD) is a common acquired valvulopathy, which carries a
high burden of mortality. Chronic inflammation has been postulated as the predominant …

The aortic valve (AV) experiences a complex mechanical environment, which includes
tension, flexure, pressure, and shear stress forces due to blood flow during each cardiac …