Myocardial fibrosis is a feature found in most cardiac diseases and a key element
contributing to heart failure and its progression. It has therefore become a subject of …

Myocardial fibrosis is the villain of sudden cardiac death. Myocardial ischemia/reperfusion
(MI/R) injury induces cardiomyocyte damage or even death, which in turn stimulates …

Hydrogen sulfide (H2S) promotes microangiogenesis and revascularization after ischemia.
Neovascularization starts with the destruction of intercellular junctions and is accompanied …

Abstract Aims Cyclophilin A (CyPA) induces leucocyte recruitment and platelet activation
upon release into the extracellular space. Extracellular CyPA therefore plays a critical role in …

Abstract AMP-activated protein kinase (5'-adenosine monophosphate-activated protein
kinase, AMPK)/mammalian target of rapamycin (mTOR) is an important signaling pathway …

Left ventricle remodeling (LVR) after acute myocardial infarction (aMI) leads to impairment of
both systolic and diastolic function, a major contributor to heart failure (HF). Despite …

This study aimed to explore the effects of peroxisome proliferator-activated receptor α (PPAR-
α), a known inhibitor of ferroptosis, in Myocardial ischemia/reperfusion injury (MIRI) and its …

Background Gestational diabetes mellitus (GDM) is associated with adverse myocardial
remodeling and impaired cardiac function of fetus. Nevertheless, specific molecular …

Myeloid-derived suppressor cells (MDSCs) are important participants after acute myocardial
infarction (AMI), but the role of their different subtypes in AMI remains controversial. The anti …

Die koronare Herzerkrankung (KHK) und darunter ihre schwerwiegendste Komplikation, der
akute Myokardinfarkt, stellen heute die häufigste Todesursache weltweit dar. Insgesamt sind …