[HTML][HTML] Papillary thyroid cancer—Aggressive variants and impact on management: A narrative review

A Coca-Pelaz, JP Shah, JC Hernandez-Prera… - Advances in …, 2020 - Springer
Introduction Aggressive variants of papillary thyroid cancer (PTC) have been described with
increasing frequency. These variants include diffuse sclerosing variant, tall cell variant …

[HTML][HTML] Updates in the pathologic classification of thyroid neoplasms: a review of the World Health Organization classification

Y Bai, K Kakudo, CK Jung - Endocrinology and Metabolism, 2020 - synapse.koreamed.org
Advances in medical sciences and evidence-based medicine have led to momentous
changes in classification and management of thyroid neoplasms. Much progress has been …

[HTML][HTML] Association between TERT promoter mutations and clinical behaviors in differentiated thyroid carcinoma: a systematic review and meta-analysis

J Yang, Y Gong, S Yan, H Chen, S Qin, R Gong - Endocrine, 2020 - Springer
Background The association between telomerase reverse transcriptase (TERT) promoter
mutations and some clinical behaviors in thyroid cancer remains controversial and requires …

[HTML][HTML] A shift in molecular drivers of papillary thyroid carcinoma following the 2017 World health organization classification: characterization of 554 consecutive …

JF Hang, JY Chen, PC Kuo, HF Lai, TL Lee, SK Tai… - Modern Pathology, 2023 - Elsevier
Most studies for comprehensive molecular profiling of papillary thyroid carcinoma (PTC)
have been performed before the 2017 World Health Organization (WHO) classification, in …

Molecular Pathology of Non-familial Follicular Epithelial–Derived Thyroid Cancer in Adults: From RAS/BRAF-like Tumor Designations to Molecular Risk Stratification

P Soares, AA Povoa, M Melo, J Vinagre, V Maximo… - Endocrine …, 2021 - Springer
This review addresses the impact of molecular alterations on the diagnosis and prognosis of
differentiated thyroid carcinoma (DTC), including papillary, follicular, and well-differentiated …

[HTML][HTML] Genetic profiles of aggressive variants of papillary thyroid carcinomas

M Jin, DE Song, J Ahn, E Song, YM Lee, TY Sung… - Cancers, 2021 - mdpi.com
Simple Summary Aggressive variants of papillary thyroid carcinoma (PTC) are associated
with unfavorable clinical outcomes. However, limited data exist on the genetic profile of …

Tall cell percentage alone in PTC without aggressive features should not guide patients' clinical management

AM Poma, D Viola, E Macerola, A Proietti… - The Journal of …, 2021 - academic.oup.com
Context Recent diagnostic criteria updates of the tall cell variant of papillary thyroid
carcinoma (TCPTC) by the World Health Organization (WHO) have determined the inclusion …

[HTML][HTML] Predictive factors indicative of hemithyroidectomy and close follow-up versus bilateral total thyroidectomy for aggressive variants of papillary thyroid cancer

IA Lee, G Moon, S Kang, KH Lee, SM Lee, JK Kim… - Cancers, 2022 - mdpi.com
Simple Summary This study evaluated the need for additional surgical treatment in patients
diagnosed with aggressive variants of papillary thyroid cancer after lobectomy. With the …

Papillary thyroid carcinoma tall cell variant shares accumulation of mitochondria, mitochondrial DNA mutations, and loss of oxidative phosphorylation complex I …

O Tsybrovskyy, M De Luise, D de Biase… - The Journal of …, 2022 - Wiley Online Library
Papillary thyroid carcinoma tall cell variant (PTC‐TCV), a form of PTC regarded as an
aggressive subtype, shares several morphologic features with oncocytic tumors. Pathogenic …

[HTML][HTML] A Critical Assessment of Diagnostic Criteria for the Tall Cell Subtype of Papillary Thyroid Carcinoma—How Much? How Tall? And When Is It Relevant?

J Turchini, TL Fuchs, A Chou, L Sioson, A Clarkson… - Endocrine …, 2023 - Springer
Tall cell papillary thyroid carcinoma (TC-PTC) is considered adverse histology. However,
previous studies are confounded by inconsistent criteria and strong associations with other …