[HTML][HTML] Pathophysiology of chemotherapy-induced peripheral neuropathy

H Starobova, I Vetter - Frontiers in molecular neuroscience, 2017 - frontiersin.org
Chemotherapy-induced neuropathy is a common, dose-dependent adverse effect of several
antineoplastics. It can lead to detrimental dose reductions and discontinuation of treatment …

Chemotherapy‐induced peripheral neurotoxicity: a critical analysis

SB Park, D Goldstein, AV Krishnan… - CA: a cancer journal …, 2013 - Wiley Online Library
With a 3‐fold increase in the number of cancer survivors noted since the 1970s, there are
now over 28 million cancer survivors worldwide. Accordingly, there is a heightened …

Prevention and management of chemotherapy-induced peripheral neuropathy in survivors of adult cancers: ASCO guideline update

CL Loprinzi, C Lacchetti, J Bleeker… - Journal of Clinical …, 2020 - ascopubs.org
PURPOSE To update the ASCO guideline on the recommended prevention and treatment
approaches in the management of chemotherapy-induced peripheral neuropathy (CIPN) in …

Colon cancer, version 2.2021, NCCN clinical practice guidelines in oncology

AB Benson, AP Venook, MM Al-Hawary… - Journal of the National …, 2021 - jnccn.org
This selection from the NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines)
for Colon Cancer focuses on systemic therapy options for the treatment of metastatic …

[HTML][HTML] Pathobiology of cancer chemotherapy-induced peripheral neuropathy (CIPN)

Y Han, MT Smith - Frontiers in pharmacology, 2013 - frontiersin.org
Chemotherapy induced peripheral neuropathy (CIPN) is a type of neuropathic pain that is a
major dose-limiting side-effect of potentially curative cancer chemotherapy treatment …

[HTML][HTML] Magnesium and pain

HJ Shin, HS Na, SH Do - Nutrients, 2020 - mdpi.com
In terms of antinociceptive action, the main mode of action of magnesium involves its
antagonist action at the N-methyl-d-aspartate (NMDA) receptor, which prevents central …

Interventions for preventing neuropathy caused by cisplatin and related compounds

JW Albers, V Chaudhry, G Cavaletti… - Cochrane Database …, 2014 - cochranelibrary.com
Background Cisplatin and several related antineoplastic drugs used to treat many types of
solid tumours are neurotoxic, and most patients completing a full course of cisplatin …

Colon cancer, version 3.2014

AB Benson, AP Venook, T Bekaii-Saab, E Chan… - Journal of the National …, 2014 - jnccn.org
The NCCN Guidelines for Colon Cancer address diagnosis, pathologic staging, surgical
management, perioperative treatment, posttreatment surveillance, management of recurrent …

[HTML][HTML] Magnesium-to-calcium ratio and mortality from COVID-19

F Guerrero-Romero, M Mercado, M Rodriguez-Moran… - Nutrients, 2022 - mdpi.com
Obesity, type 2 diabetes, arterial hypertension, decrease in immune response, cytokine
storm, endothelial dysfunction, and arrhythmias, which are frequent in COVID-19 patients …

Preventive effect of Goshajinkigan on peripheral neurotoxicity of FOLFOX therapy (GENIUS trial): a placebo-controlled, double-blind, randomized phase III study

E Oki, Y Emi, H Kojima, J Higashijima, T Kato… - International Journal of …, 2015 - Springer
Background Peripheral sensory neurotoxicity is a frequent adverse effect of oxaliplatin
therapy. Calcium and magnesium (Ca/Mg) infusions are frequently used as preventatives …