P174E substitution in GES-1 and GES-5 β-lactamases improves catalytic efficiency toward carbapenems

A Piccirilli, PS Mercuri, M Galleni, M Aschi… - Antimicrobial Agents …, 2018 - Am Soc Microbiol
ABSTRACT GES-type β-lactamases are a group of enzymes that have evolved their
hydrolytic activity against carbapenems. In this study, the role of residue 174 inside the Ω …

One lead to numerous: A DNA concatemer-based fluorescence aptasensor for selective and sensitive Acinetobacter baumannii detection

L Li, J Tan, C Zhang, X Ding, T Wu, Y Shi, T Chen… - Microchemical …, 2023 - Elsevier
Rapid and precise analysis of Acinetobacter baumannii plays a crucial role in inhibition of
healthcare-associated infectious diseases and development of optimal treatment strategies …

An Update on Colistin in Clinical Healthcare Unit in the Kingdom of Saudi Arabia: A Narrative Review

H Faidah - Current Pharmaceutical Design, 2024 - benthamdirect.com
Globally, gram-negative bacteria are a significant cause of morbidity. Multi-drug resistance
bacteria are responsible for an increasing surge in infections that place a high cost on …

Bacteriological profile of wound infections and antimicrobial resistance in selected gram-negative bacteria

A Bandy, FA Wani, AH Mohammed, UF Dar… - African Health …, 2022 - ajol.info
Background: Managing wound infections is a challenging task. Understanding their
resistance pattern is an essential step at reducing its burden in hospital settings. Objective …

A novel mutation in pmrB mediates colistin resistance during therapy of Acinetobacter baumannii

E Dahdouh, R Gómez-Gil, S Sanz… - International journal of …, 2017 - Elsevier
Acinetobacter baumannii is a highly versatile nosocomial pathogen. Multidrug resistance
among A. baumannii isolates led to the use of colistin, subsequently giving rise to colistin …

Antimicrobial Resistance of Serial Isolates of Acinetobacter baumannii Colonizing the Rectum of Adult Intensive Care Unit Patients in a Teaching Hospital in Kuwait

G Al-Hashem, VO Rotimi, MJ Albert - Microbial Drug Resistance, 2021 - liebertpub.com
Objectives: Outbreak and endemic isolates of Acinetobacter baumannii are known to be
polyclonal. In an ongoing study, we hypothesized that the patient gut was the source of the …

Novel class 1 integron (In1390) harboring blaGES-5 in a Morganella morganii strain recovered from a remote community

Q Moura, L Cerdeira, MR Fernandes… - … and Infectious Disease, 2018 - Elsevier
Antimicrobial resistance in Morganella morganii has been mainly acquired via plasmids and
class 1 integrons. We hereby report acquisition of bla GES-5 by a M. morganii isolated in a …

Surveillance of carbapenem-resistant Klebsiella pneumoniae in a paediatric hospital in China revealed the dynamics of carbapenemase and the prevalence of …

Y Zhou, Z Zhao, L Zeng, J Peng… - Journal of Medical …, 2022 - microbiologyresearch.org
Background. Carbapenem-resistant Klebsiella pneumoniae (CRKP) is increasingly isolated
in paediatric wards, posing a severe threat to these vulnerable populations. This study …

[PDF][PDF] The Prevalence of Multidrug-Resistant Acinetobacter baumannii and Its Vaccination Status among Healthcare Providers. Vaccines 2023, 11, 1171. h ps

A Elbehiry, E Marzouk, I Moussa… - doi. org/10.3390 …, 2023 - researchgate.net
There is growing concern among healthcare providers worldwide regarding the prevalence
of multidrug-resistant Acinetobacter baumannii (A. baumannii). Some of the worst hospital …

[PDF][PDF] Emerging status of multidrug-resistant bacteria and fungi in the arabian peninsula. Biology 2021; 10: 1144

JF Borgio, AS Rasdan, B Sonbol, G Alhamid… - 2021 - academia.edu
We aimed to identify the prevalence and emerging status of multidrug-resistant bacteria and
fungi and their associated mortality in nine countries in the Arabian Peninsula. Original …