Pulmonary fibrosis is a pathologic process associated with scarring of the lung interstitium.
Interstitial lung diseases (ILDs) encompass a large and heterogenous group of disorders, a …

Brown adipose tissue (BAT) controls mammalian core body temperature by non-shivering
thermogenesis. BAT is extraordinarily rich in mitochondria, which have the peculiarity of …

Background: Excess cholesterol accumulation in lesional macrophages elicits complex
responses in atherosclerosis. Epsins, a family of endocytic adaptors, fuel the progression of …

BACKGROUND: Efferocytosis is an activity of macrophages that is pivotal for the resolution
of inflammation in hypertension. The precise mechanism by which macrophages coordinate …

Phagocytosis is a fundamental immunobiological process responsible for the removal of
harmful particulates. While the number of phagocytic events achieved by a single phagocyte …

Macrophages release soluble mediators following efferocytic clearance of apoptotic cells to
facilitate intercellular communication and promote the resolution of inflammation. However …

BACKGROUND: Atherosclerotic plaques are complex tissues composed of a
heterogeneous mixture of cells. However, our understanding of the comprehensive …

Asthma is a heterogenous chronic inflammatory lung disease with endotypes that manifest
different immune system profiles, severity, and responses to current therapies. Regardless of …

With the changing disease spectrum, atherosclerosis has become increasingly prevalent
worldwide and the associated diseases have emerged as the leading cause of death. Due …

Innate immunity triggered by the cGAS/STING pathway has the potential to improve cancer
immunotherapy. Previously, the authors reported that double‐stranded DNA (dsDNA) …