Major histocompatibility complex (MHC) is a conglomerate of genes that play an important
role in recognition of self and nonself. These genes are under tight control. In this review we …

The replicative cycle of HIV presents several events. The proteins involved in these events
can be anticipated as pharmacological targets, aiming to the development of anti viral …

Most chronic viruses evade T-cell and natural killer (NK) immunity through downregulation
of immune surface markers. Previously we showed that Pomalidomide (Pom) increases …

Many pathogens have co‐evolved with their human hosts to develop strategies for immune
evasion that involve disruption of the intra‐cellular pathways by which antigens are bound …

The HIV-1 accessory protein Nef is well known for its manipulation of host cell endosomal
trafficking. By linking transmembrane proteins to endosomal coats, Nef removes them from …

Solid‐state nmr spectroscopy provides a robust method for investigating polypeptides that
have been prepared by chemical synthesis and that are immobilized by strong interactions …

As is the case in other viral infections, humans respond to HIV infection by activating their
NK cells. However, the virus uses several strategies to neutralize and evade the host's NK …

ABSTRACT HFE is a nonclassical class I major histocompatibility complex (MHC) molecule
that is mutated in the autosomal recessive iron overload disease hereditary …

In 1985, a group of healthy Senegalese whose sera demonstrated much stronger antibody
responses to simian immunodeficiency virus (SIV) than to the HIV type 1 (HIV-1) was first …

The structure of the membrane anchor domain (VpuMA) of the HIV-1-specific accessory
protein Vpu has been investigated in solution and in lipid bilayers by homonuclear two …