Selenium, iodine and iron–essential trace elements for thyroid hormone synthesis and metabolism

J Köhrle - International journal of molecular sciences, 2023 - mdpi.com
The adequate availability and metabolism of three essential trace elements, iodine,
selenium and iron, provide the basic requirements for the function and action of the thyroid …

Zooming in and out of ferroptosis in human disease

X Wang, Y Zhou, J Min, F Wang - Frontiers of Medicine, 2023 - Springer
Ferroptosis is defined as an iron-dependent regulated form of cell death driven by lipid
peroxidation. In the past decade, it has been implicated in the pathogenesis of various …

Primary hypothyroidism and Alzheimer's Disease: a tale of two

FH AlAnazi, HM Al-Kuraishy, A Alexiou… - Cellular and Molecular …, 2023 - Springer
Hypothyroidism (HPT) HPT could be a risk factor for the development and progression of
Alzheimer's disease (AD). In addition, progressive neurodegeneration in AD may affect the …

Green Pea (Pisum sativum L.) Hull Polyphenol Extract Alleviates NAFLD through VB6/TLR4/NF-κB and PPAR Pathways

F Guo, H Xiong, R Tsao, F Shahidi, X Wen… - Journal of Agricultural …, 2023 - ACS Publications
Green pea hull is a processing byproduct of green pea and rich in polyphenols.
Nonalcoholic fatty liver disease (NAFLD) is a chronic metabolic disease characterized by …

The emerging role of ferroptosis in liver diseases

S Chen, J Zhu, X Zang, Y Zhai - Frontiers in Cell and Developmental …, 2021 - frontiersin.org
Ferroptosis is a newly discovered type of cell death mediated by iron-dependent lipid
peroxide. The disturbance of iron metabolism, imbalance of the amino acid antioxidant …

Inhibition of free heme-catalyzed Fenton-like reaction prevents non-alcoholic fatty liver disease by hepatocyte-targeted hydrogen delivery

M Zhao, Z Jin, C Xia, S Chen, L Zeng, S Qin, Q He - Biomaterials, 2023 - Elsevier
The metabolic disorder of hepatocytes in non-alcoholic fatty liver disease (NAFLD) leads to
the formation of an iron pool which induces the Fenton reaction-derived ferroptosis and the …

[HTML][HTML] Melatonin alleviates cadmium-induced nonalcoholic fatty liver disease in ducks by alleviating autophagic flow arrest via PPAR-α and reducing oxidative stress

J Sun, Y Bian, Y Ma, W Ali, T Wang, Y Yuan, J Gu… - Poultry Science, 2023 - Elsevier
Cadmium (Cd) is an important environmental pollutant that causes liver damage and
induces nonalcoholic fatty liver disease (NAFLD). NAFLD is a fat accumulation disease and …

Lipid metabolism, BMI and the risk of nonalcoholic fatty liver disease in the general population: evidence from a mediation analysis

S Lu, Q Xie, M Kuang, C Hu, X Li, H Yang… - Journal of Translational …, 2023 - Springer
Background Body mass index (BMI) and lipid parameters are the most commonly used
anthropometric parameters and biomarkers for assessing nonalcoholic fatty liver disease …

[HTML][HTML] Arbutin alleviates fatty liver by inhibiting ferroptosis via FTO/SLC7A11 pathway

T Jiang, Y Xiao, J Zhou, Z Luo, L Yu, Q Liao, S Liu, X Qi… - Redox Biology, 2023 - Elsevier
Non-alcoholic fatty liver disease (NAFLD) is a potentially serious disease that affects 30% of
the global population and poses a significant risk to human health. However, to date, no …

[HTML][HTML] Selenomethionine alleviates environmental heat stress induced hepatic lipid accumulation and glycogen infiltration of broilers via maintaining mitochondrial …

J Jing, H Zeng, Q Shao, J Tang, L Wang, G Jia, G Liu… - Redox Biology, 2023 - Elsevier
With the increasing of global mean surface air temperature, heat stress (HS) induced by
extreme high temperature has become a key factor restricting the poultry industry. Liver is …