[HTML][HTML] A comprehensive review of rosmarinic acid: from phytochemistry to pharmacology and its new insight

H Guan, W Luo, B Bao, Y Cao, F Cheng, S Yu, Q Fan… - Molecules, 2022 - mdpi.com
Polyphenolic acids are the widely occurring natural products in almost each herbal plant,
among which rosmarinic acid (RA, C18H16O8) is well-known, and is present in over 160 …

[HTML][HTML] Therapeutic potential of rosmarinic acid: A comprehensive review

M Nadeem, M Imran, T Aslam Gondal, A Imran… - Applied Sciences, 2019 - mdpi.com
Naturally occurring food-derived active ingredients have received huge attention for their
chemopreventive and chemotherapy capabilities in several diseases. Rosmarinic acid (RA) …

[HTML][HTML] Rosmarinic acid–pharmaceutical and clinical aspects

SKS Amoah, LP Sandjo, JM Kratz, MW Biavatti - Planta medica, 2016 - thieme-connect.com
The biosynthesis and biotechnological production of Rosmarinic acid, a phenolic ester that
is widespread in the plant kingdom, has been widely investigated. This compound has …

[HTML][HTML] Rosmarinic acid and its derivatives: Current insights on anticancer potential and other biomedical applications

S Ijaz, J Iqbal, BA Abbasi, Z Ullah, T Yaseen… - Biomedicine & …, 2023 - Elsevier
Cancer is still the leading cause of death worldwide, burdening the global medical system.
Rosmarinic acid (RA) is among the first secondary metabolites discovered and it is a …

[HTML][HTML] Rosmarinic acid suppresses Alzheimer's disease development by reducing amyloid β aggregation by increasing monoamine secretion

T Hase, S Shishido, S Yamamoto, R Yamashita… - Scientific Reports, 2019 - nature.com
A new mechanism is revealed by which a polyphenol, rosmarinic acid (RA), suppresses
amyloid β (Aβ) accumulation in mice. Here we examined the brains of mice (Alzheimer's …

[HTML][HTML] Powerful plant antioxidants: A new biosustainable approach to the production of rosmarinic acid

A Khojasteh, MH Mirjalili, MA Alcalde, RM Cusido… - Antioxidants, 2020 - mdpi.com
Modern lifestyle factors, such as physical inactivity, obesity, smoking, and exposure to
environmental pollution, induce excessive generation of free radicals and reactive oxygen …

Therapeutic and nutraceutical potential of rosmarinic acid—Cytoprotective properties and pharmacokinetic profile

S Nunes, AR Madureira, D Campos… - Critical reviews in …, 2017 - Taylor & Francis
Rosmarinic acid (RA) is a natural polyphenolic antioxidant derived from many common
herbal plants. This compound displays several important biological properties, including anti …

[HTML][HTML] Hepatoprotective effects of rosmarinic acid: Insight into its mechanisms of action

TO Elufioye, S Habtemariam - Biomedicine & Pharmacotherapy, 2019 - Elsevier
Liver diseases such as hepatitis, fibrosis, cirrhosis, and hepatocellular carcinoma are one of
the major health challenges in the world and many conditions such as inadequate nutrition …

Rosmarinic acid and its derivatives: biotechnology and applications

VP Bulgakov, YV Inyushkina… - Critical reviews in …, 2012 - Taylor & Francis
Rosmarinic acid (RA) is one of the first secondary metabolites produced in plant cell cultures
in extremely high yields, up to 19% of the cell dry weight. More complex derivatives of RA …

Rosmarinic acid ameliorates acute liver damage and fibrogenesis in carbon tetrachloride-intoxicated mice

R Domitrović, M Škoda, VV Marchesi… - Food and chemical …, 2013 - Elsevier
The aim of this study was to investigate the therapeutic potential of rosmarinic acid (RA), a
natural phenolic, in the treatment of acute liver toxicity. RA at 10, 25 and 50mg/kg was …