Natural bio-active compounds
Secondary metabolites are the unique faction of compounds, produced by plants to protect
itself against the various biotic and abiotic factors (diseases, pests, pathogens, herbivores …
itself against the various biotic and abiotic factors (diseases, pests, pathogens, herbivores …
[HTML][HTML] Zingiber officinale acts as a nutraceutical agent against liver fibrosis
Abstract Background/objective Zingiber officinale Roscoe (ginger)(Zingiberaceae) has been
cultivated for thousands of years both as a spice and for medicinal purposes. Ginger …
cultivated for thousands of years both as a spice and for medicinal purposes. Ginger …
Human precision-cut liver slices as a model to test antifibrotic drugs in the early onset of liver fibrosis
IM Westra, HAM Mutsaers, T Luangmonkong, M Hadi… - Toxicology In Vitro, 2016 - Elsevier
Liver fibrosis is the progressive accumulation of connective tissue ultimately resulting in loss
of organ function. Currently, no effective antifibrotics are available due to a lack of reliable …
of organ function. Currently, no effective antifibrotics are available due to a lack of reliable …
Relevance of carnosic acid to the treatment of several health disorders: Molecular targets and mechanisms
S Bahri, S Jameleddine, V Shlyonsky - Biomedicine & pharmacotherapy, 2016 - Elsevier
Carnosic acid is a phenolic diterperne compound found in abundance in sage and
rosemary, which are both widely used in traditional medicine. Research over the past …
rosemary, which are both widely used in traditional medicine. Research over the past …
[HTML][HTML] Hepatoprotective potential of Rosmarinus officinalis essential oil against hexavalent chromium-induced hematotoxicity, biochemical, histological, and …
FM El-Demerdash, RA El-Sayed… - … Science and Pollution …, 2021 - Springer
Hexavalent chromium (Cr VI) is widely known as a potential hepatotoxic in humans and
animals and its toxicity is associated with oxidative stress. So, an in vivo study was outlined …
animals and its toxicity is associated with oxidative stress. So, an in vivo study was outlined …
Antifibrotic activity of galangin, a novel function evaluated in animal liver fibrosis model
X Wang, G Gong, W Yang, Y Li, M Jiang, L Li - Environmental Toxicology …, 2013 - Elsevier
This study aimed to investigate the effects of galangin on liver fibrosis in rats induced by
subcutaneous injection of carbon tetrachloride (CCl 4). The administration of CCl 4 to rats for …
subcutaneous injection of carbon tetrachloride (CCl 4). The administration of CCl 4 to rats for …
Enrichment of rosmarinic acid from Salvia przewalskii Maxim. leaves using macroporous resin: Adsorption/desorption behavior, process optimization followed by scale …
Q Fan, Y Li - Industrial Crops and Products, 2023 - Elsevier
Abstract To valorize Salvia przewalskii Maxim. leaves as a renewable source of rosmarinic
acid, an efficient macroporous resin enrichment technology was established in this work. X-5 …
acid, an efficient macroporous resin enrichment technology was established in this work. X-5 …
[HTML][HTML] Rosmarinic acid ameliorates renal interstitial fibrosis by inhibiting the phosphorylated-AKT mediated epithelial–mesenchymal transition in vitro and in vivo
YH Hsieh, JP Tsai, YH Ting, TW Hung, WW Chao - Food & Function, 2022 - pubs.rsc.org
Indoxyl sulfate (IS), a uremic toxin, causes chronic kidney disease (CKD) progression via
renal fibrosis. Epithelial–mesenchymal transition (EMT) is a crucial feature of renal fibrosis …
renal fibrosis. Epithelial–mesenchymal transition (EMT) is a crucial feature of renal fibrosis …
Antioxidant and antigenotoxic effects of rosemary (Rosmarinus officinalis L.) extracts in Salmonella typhimurium TA98 and HepG2 cells
In the present study the chemopreventive effects of water soluble AquaROX® 15 and oil
soluble VivOX® 40 rosemary extracts against 4-nitroquinoline-N-oxide (NQNO) and 2-amino …
soluble VivOX® 40 rosemary extracts against 4-nitroquinoline-N-oxide (NQNO) and 2-amino …
[HTML][HTML] Rosmarinic acid prevents post-operative abdominal adhesions in a rat model
A Kakanezhadi, M Rezaei, A Raisi, O Dezfoulian… - Scientific Reports, 2022 - nature.com
This study aims to determine the effects of rosmarinic acid which involved the mechanisms
to decrease the postoperative peritoneal adhesion formation in rats. Various incisions and …
to decrease the postoperative peritoneal adhesion formation in rats. Various incisions and …