Copper homeostasis and copper-induced cell death in the pathogenesis of cardiovascular disease and therapeutic strategies

X Chen, Q Cai, R Liang, D Zhang, X Liu, M Zhang… - Cell death & …, 2023 - nature.com
Copper is a vital mineral, and an optimal amount of copper is required to support normal
physiologic processes in various systems, including the cardiovascular system. Over the …

Mechanisms of diabetic cardiomyopathy and potential therapeutic strategies: preclinical and clinical evidence

Y Tan, Z Zhang, C Zheng, KA Wintergerst… - Nature Reviews …, 2020 - nature.com
The pathogenesis and clinical features of diabetic cardiomyopathy have been well-studied
in the past decade, but effective approaches to prevent and treat this disease are limited …

[HTML][HTML] Associations of plasma metal concentrations with the risks of all-cause and cardiovascular disease mortality in Chinese adults

L Shi, Y Yuan, Y Xiao, P Long, W Li, Y Yu, Y Liu… - Environment …, 2021 - Elsevier
Background Exposure to metals/metalloids from both the natural environment and
anthropogenic sources have a complex influence on human health. However, relatively few …

Selenium, Copper, Zinc Concentrations and Cu/Zn, Cu/Se Molar Ratios in the serum of patients with acute ischemic stroke in Northeastern Poland—a new insight into …

A Mirończuk, K Kapica-Topczewska, K Socha… - Nutrients, 2021 - mdpi.com
Background: In recent years, trace elements (TEs) have gained considerable attention in the
course of treatment and diagnosis of ischemic stroke. The purpose of the conducted …

Association of zinc deficiency with development of CVD events in patients with CKD

S Nakatani, K Mori, T Shoji, M Emoto - Nutrients, 2021 - mdpi.com
Deficiency of the micronutrient zinc is common in patients with chronic kidney disease
(CKD). The aim of this review is to summarize evidence presented in literature for …

New progress in early diagnosis of atherosclerosis

H Meng, J Ruan, Z Yan, Y Chen, J Liu, X Li… - International Journal of …, 2022 - mdpi.com
Coronary atherosclerosis is a potentially chronic circulatory condition that endangers human
health. The biological cause underpinning cardiovascular disease is coronary …

Association between dietary zinc intake and abdominal aortic calcification in US adults

W Chen, R Eisenberg, WB Mowrey… - Nephrology Dialysis …, 2020 - academic.oup.com
Background In animal studies, zinc supplementation inhibited phosphate-induced arterial
calcification. We tested the hypothesis that higher intake of dietary zinc was associated with …

Circulating multiple metals and incident stroke in Chinese adults: the Dongfeng-Tongji cohort

Y Xiao, Y Yuan, Y Liu, Y Yu, N Jia, L Zhou, H Wang… - Stroke, 2019 - Am Heart Assoc
Background and Purpose—Circulating metals synchronously reflect multiple metal
exposures from both natural and anthropogenic sources, which may be linked with the risk …

Zinc intake and status and risk of type 2 diabetes mellitus: a systematic review and meta-analysis

JC Fernández-Cao, M Warthon-Medina, V H. Moran… - Nutrients, 2019 - mdpi.com
Zinc could have a protective role against type 2 diabetes mellitus (T2DM). This systematic
review and meta-analysis aimed to evaluate the association between dietary …

[HTML][HTML] Redox and metal profiles in human coronary endothelial and smooth muscle cells under hyperoxia, physiological normoxia and hypoxia: Effects of NRF2 …

MJ Smith, F Yang, A Griffiths, A Morrell, SJ Chapple… - Redox Biology, 2023 - Elsevier
Zinc is an important component of cellular antioxidant defenses and dysregulation of zinc
homeostasis is a risk factor for coronary heart disease and ischemia/reperfusion injury …