Since the 19th century the phytochemistry of the Salicaceae has been systematically
investigated, initially for pharmaceutical and later for ecological reasons. The result of these …

The biopharmaceutical properties—especially the solubility and permeability—of a molecule
contribute to its overall therapeutic efficacy. The newer tools of drug discovery have caused …

It is now just about 10 years since the publication of the first edition of Polymorphism in
Pharmaceutical Solids, which certainly received a positive reaction from workers in drug …

The physical state of a dosage form, crystalline versus amorphous, is critical in determining
its solid‐state physical and chemical properties. This minireview describes the physics …

Purpose. The objective was to develop a single-step pharmaceutical particle engineering
technique able to produce particles within a well-defined particle size range while …

The objective of this study was to investigate the influence of the starting solid state form of
piroxicam (anhydrate form I: PRXAH I vs form II: PRXAH II) on the properties of the resulting …

Abbott‐232 is a chemically stable, highly water soluble non‐hygroscopic compound
selected for development as a potent uroselective α1A agonist. An anhydrate, a …

The most common drawback of the existing and novel drug molecules is their low
bioavailability because of their low solubility. One of the most important approaches to …

This special issue of Pharmaceutical Research is dedicated to Professor Kenneth R. Morris,
who for more than 3 decades has been a leader in research devoted to the interplay …

Purpose To develop a calorimetry-based model for estimating the time-dependence of
molecular mobility during the isothermal relaxation of amorphous organic compounds below …