[HTML][HTML] Mechanisms contributing to the comorbidity of COPD and lung cancer
Lung cancer and chronic obstructive pulmonary disease (COPD) often co-occur, and
individuals with COPD are at a higher risk of developing lung cancer. While the underlying …
individuals with COPD are at a higher risk of developing lung cancer. While the underlying …
[HTML][HTML] Airway microbiome-immune crosstalk in chronic obstructive pulmonary disease
Chronic Obstructive Pulmonary Disease (COPD) has significantly contributed to global
mortality, with three million deaths reported annually. This impact is expected to increase …
mortality, with three million deaths reported annually. This impact is expected to increase …
[HTML][HTML] Circulating microRNA signatures associated with disease severity and outcome in COVID-19 patients
A Giannella, S Riccetti, A Sinigaglia, C Piubelli… - Frontiers in …, 2022 - frontiersin.org
Background SARS-CoV-2 induces a spectrum of clinical conditions ranging from
asymptomatic infection to life threatening severe disease. Host microRNAs have been …
asymptomatic infection to life threatening severe disease. Host microRNAs have been …
[PDF][PDF] Role of oxidative stress in the pathogenesis of COPD
Chronic inhalation of cigarette smoke is a prominent cause of chronic obstructive pulmonary
disease (COPD) and provides an important source of exogenous oxidants. In addition …
disease (COPD) and provides an important source of exogenous oxidants. In addition …
Long-term cadmium exposure induces chronic obstructive pulmonary disease-like lung lesions in a mouse model
WJ Wang, K Peng, X Lu, YY Zhu, Z Li, QH Qian… - Science of The Total …, 2023 - Elsevier
Accumulating evidences demonstrate that long-term exposure to atmospheric fine particles
and air pollutants elevates the risk of chronic obstructive pulmonary disease (COPD) …
and air pollutants elevates the risk of chronic obstructive pulmonary disease (COPD) …
Adverse roles of mast cell chymase-1 in COPD
Background COPD is the third leading cause of death worldwide. Cigarette smoke (CS)-
induced chronic inflammation inducing airway remodelling, emphysema and impaired lung …
induced chronic inflammation inducing airway remodelling, emphysema and impaired lung …
[HTML][HTML] TLR7 promotes smoke-induced experimental lung damage through the activity of mast cell tryptase
Abstract Toll-like receptor 7 (TLR7) is known for eliciting immunity against single-stranded
RNA viruses, and is increased in both human and cigarette smoke (CS)-induced …
RNA viruses, and is increased in both human and cigarette smoke (CS)-induced …
RIPK1 kinase-dependent inflammation and cell death contribute to the pathogenesis of COPD
Background Receptor-interacting protein kinase 1 (RIPK1) is a key mediator of regulated
cell death (including apoptosis and necroptosis) and inflammation, both drivers of COPD …
cell death (including apoptosis and necroptosis) and inflammation, both drivers of COPD …
[HTML][HTML] Systemic alterations in neutrophils and their precursors in early-stage chronic obstructive pulmonary disease
Systemic inflammation is established as part of late-stage severe lung disease, but
molecular, functional, and phenotypic changes in peripheral immune cells in early disease …
molecular, functional, and phenotypic changes in peripheral immune cells in early disease …
Smoking and tetramer tryptase accelerate intervertebral disc degeneration by inducing METTL14-mediated DIXDC1 m6 modification
Although cigarette smoking (CS) and low back pain (LBP) are common worldwide, their
correlations and the mechanisms of action remain unclear. We have shown that excessive …
correlations and the mechanisms of action remain unclear. We have shown that excessive …