Effect of β-amyloid on blood-brain barrier properties and function
IY Petrushanko, VA Mitkevich, AA Makarov - Biophysical Reviews, 2023 - Springer
The deposition of beta-amyloid (Aβ) aggregates in the brain, accompanied by impaired
cognitive function, is a characteristic feature of Alzheimer's disease (AD). An important role …
cognitive function, is a characteristic feature of Alzheimer's disease (AD). An important role …
Papel de los antioxidantes en la prevención del cáncer
L Llacuna, N Mach - Revista Española de Nutrición Humana y Dietética, 2012 - Elsevier
La naturaleza de la asociación entre radicales libres y cáncer es compleja y paradójica.
Parece que los radicales libres y el estrés oxidativo pueden inducir cáncer, pero al mismo …
Parece que los radicales libres y el estrés oxidativo pueden inducir cáncer, pero al mismo …
[HTML][HTML] Mechanistic basis for protection of differentiated SH-SY5Y cells by oryzanol-rich fraction against hydrogen peroxide-induced neurotoxicity
Background Apoptosis is often the end result of oxidative damage to neurons. Due to shared
pathways between oxidative stress, apoptosis and antioxidant defence systems, an …
pathways between oxidative stress, apoptosis and antioxidant defence systems, an …
Synthetic and Natural Bioactive Molecules in Balancing the Crosstalk among Common Signaling Pathways in Alzheimer's Disease: Understanding the Neurotoxic …
The structure and function of the brain greatly rely on different signaling pathways. The wide
variety of biological processes, including neurogenesis, axonal remodeling, the …
variety of biological processes, including neurogenesis, axonal remodeling, the …
[HTML][HTML] Na, K-ATPase acts as a beta-amyloid receptor triggering src kinase activation
IY Petrushanko, AM Tverskoi, EP Barykin… - Cells, 2022 - mdpi.com
Beta-amyloid (Aβ) has a dual role, both as an important factor in the pathology of
Alzheimer's disease and as a regulator in brain physiology. The inhibitory effect of Aβ42 …
Alzheimer's disease and as a regulator in brain physiology. The inhibitory effect of Aβ42 …
[HTML][HTML] Quercetin-3-O-β-D-glucuronide suppresses lipopolysaccharide-induced JNK and ERK phosphorylation in LPS-challenged RAW264. 7 cells
JY Park, MS Lim, SI Kim, HJ Lee, SS Kim… - Biomolecules & …, 2016 - ncbi.nlm.nih.gov
Quercetin, a flavonol, has been reported to exhibit a wide range of biological properties
including anti-oxidant and anti-inflammatory activities. However, pharmacological properties …
including anti-oxidant and anti-inflammatory activities. However, pharmacological properties …
Small molecule natural products and Alzheimer's disease
X Wu, H Cai, L Pan, G Cui, F Qin… - Current topics in …, 2019 - ingentaconnect.com
Alzheimer's disease (AD) is a progressive and deadly neurodegenerative disease that is
characterized by memory loss, cognitive impairment and dementia. Several hypotheses …
characterized by memory loss, cognitive impairment and dementia. Several hypotheses …
[HTML][HTML] Cyanidin 3-O-β-glucopyranoside activates peroxisome proliferator-activated receptor-γ and alleviates cognitive impairment in the APPswe/PS1ΔE9 mouse …
N Song, L Zhang, W Chen, H Zhu, W Deng… - … et Biophysica Acta (BBA …, 2016 - Elsevier
Alzheimer's disease (AD) is currently one of the most common neurodegenerative disorders
worldwide. To date, no cure has been developed for AD, and some disease-modifying …
worldwide. To date, no cure has been developed for AD, and some disease-modifying …
Quercetin suppresses intracellular ROS formation, MMP activation, and cell motility in human fibrosarcoma cells
Cell metastasis is a major cause of death from cancer and can arise from excessive levels of
oxidative stress. The objective of this study was to investigate whether the natural flavonoid …
oxidative stress. The objective of this study was to investigate whether the natural flavonoid …
Neuroplasticity and successful cognitive aging: a brief overview for nursing
The brain remains dynamic even in older age and can benefit from mental exercises. Thus, it
is important to understand the concepts of positive and negative neuroplasticity and how …
is important to understand the concepts of positive and negative neuroplasticity and how …