[HTML][HTML] Regulations of malaria in children with human immunodeficiency virus infection: A review

AA Opeyemi, EI Obeagu - Medicine, 2023 - journals.lww.com
This comprehensive review explores the intricate relationship between 2 major global health
challenges, malaria and HIV, with a specific focus on their impact on children. These …

Two centuries of vaccination: historical and conceptual approach and future perspectives

DA Montero, RM Vidal, J Velasco, LJ Carreño… - Frontiers in public …, 2024 - frontiersin.org
Over the past two centuries, vaccines have been critical for the prevention of infectious
diseases and are considered milestones in the medical and public health history. The World …

[HTML][HTML] A phase IIa, randomized, double-blind, safety, immunogenicity and efficacy trial of Plasmodium falciparum vaccine antigens merozoite surface protein 1 and …

JF Cummings, ME Polhemus, KE Kester… - Vaccine, 2024 - Elsevier
Background To improve the efficacy of Plasmodium falciparum malaria vaccine RTS,
S/AS02, we conducted a study in 2001 in healthy, malaria-naïve adults administered RTS …

Persistence of Anti-SE36 Antibodies Induced by the Malaria Vaccine Candidate BK-SE36/CpG in 5–10-Year-Old Burkinabe Children Naturally Exposed to Malaria

I Nebie, NMQ Palacpac, EC Bougouma, A Diarra… - Vaccines, 2024 - mdpi.com
Information on the dynamics and decline/persistence of antibody titres is important in
vaccine development. A recent vaccine trial in malaria-exposed, healthy African adults and …

Targeting Plasmodium Life Cycle with Novel Parasite Ligands as Vaccine Antigens

S Khan, MP Patel, AD Patni, SJ Cha - Vaccines, 2024 - mdpi.com
The WHO reported an estimated 249 million malaria cases and 608,000 malaria deaths in
85 countries in 2022. A total of 94% of malaria deaths occurred in Africa, 80% of which were …

Breaking the malaria barrier: the WHO-approved R21/Matrix-M vaccine and its global impact–an editorial

A Verma, A Anand, VA Patel, MW Nazar… - Annals of Medicine …, 2024 - journals.lww.com
According to a recent study by the WHO in late 2021, malaria claimed~ 627 000 lives in
2020, with a child mortality rate rising from 4.8 to 7.8%[1]. The burden of malaria reached 1.7 …

Targeting Plasmodium Population Bottlenecks with Parasite Ligands as Vaccine Antigens

S Khan, MP Patel, AD Patni, SJ Cha - 2024 - preprints.org
WHO reported an estimated 249 million malaria cases and 608,000 malaria deaths in 85
countries in 2022. A total of 94% of malaria deaths occurred in Africa, 80% of which were …

MOLECULAR AND IMMUNOLOGICAL CHARACTERIZATIONS OF POTENTIALLY PROTECTIVE BLOOD-STAGE PLASMODIUM YOELII ANTIGENS

S Wiriyasirivaj, Y Mahakunkijcharoen… - … Asian Journal of …, 2023 - search.proquest.com
As malaria remains one of the world's fatal diseases, an effective malaria vaccine is urgently
required. Our previous studies have shown that formalin-killed blood-stage Plasmodium …

[PDF][PDF] The Effect of Physiology and Chemistry on Lipid Nanoparticle mRNA Delivery

M Arral - 2024 - kilthub.cmu.edu
Genetic medicine has long been heralded as the ultimate solution to most problems in
human health, including hereditary, physiological, and infectious diseases. While it sounds …

Investigating protective mechanisms of anti-sporozoite vaccines

DG Bellamy - 2023 - ora.ox.ac.uk
Malaria remains a leading cause of childhood mortality, thereby highlighting the need for an
effective vaccine. R21 is a virus-like particle-based (VLP-based) vaccine displaying the …