Mucoadhesive carriers for oral drug delivery

R Kumar, T Islam, M Nurunnabi - Journal of Controlled Release, 2022 - Elsevier
Among the various dosage forms, oral medicine has extensive benefits including ease of
administration and patients' compliance, over injectable, suppositories, ocular and nasal …

Role of nanomaterials in the fabrication of bioNEMS/MEMS for biomedical applications and towards pioneering food waste utilisation

NA Dahlan, A Thiha, F Ibrahim, L Milić, S Muniandy… - Nanomaterials, 2022 - mdpi.com
bioNEMS/MEMS has emerged as an innovative technology for the miniaturisation of
biomedical devices with high precision and rapid processing since its first R&D …

Solubility determination and three dimensional Hansen solubility parameters of gefitinib in different organic solvents: Experimental and computational approaches

A Alanazi, S Alshehri, M Altamimi, F Shakeel - Journal of Molecular Liquids, 2020 - Elsevier
Gefitinib (GFT) is an anticancer drug which shows poor aqueous solubility and
bioavailability. The quantitative solubility data of GFT in any aqueous, organic or the mixture …

c (RGDfK) anchored surface manipulated liposome for tumor-targeted Tyrosine Kinase Inhibitor (TKI) delivery to potentiate liver anticancer activity

P Deepak, P Kumar, DK Arya, P Pandey… - International Journal of …, 2023 - Elsevier
Current anticancer drug research includes tumor-targeted administration as a critical
component because it is the best strategy to boost efficacy and decrease toxicity. Low drug …

[HTML][HTML] Gefitinib loaded PLGA and chitosan coated PLGA nanoparticles with magnified cytotoxicity against A549 lung cancer cell lines

AS Alshetaili - Saudi journal of biological sciences, 2021 - Elsevier
In the current study, gefitinib loaded PLGA nanoparticles (GFT-PLGA-NPs) and chitosan
coated PLGA nanoparticles (GFT-CS-PLGA-NPs) were synthesized to investigate the role of …

p28-functionalized PLGA nanoparticles loaded with gefitinib reduce tumor burden and metastases formation on lung cancer

AR Garizo, F Castro, C Martins, A Almeida… - Journal of Controlled …, 2021 - Elsevier
Lung cancer is still the main cause of cancer-related deaths worldwide. Its treatment
generally includes surgical resection, immunotherapy, radiotherapy, and chemo-targeted …

[HTML][HTML] Design of gefitinib-loaded PLGA microspheres via microfluidics for lung cancer

R Huang, H Zhang, L Lv, Y Zhang, J Li, H Wang… - Materials & Design, 2023 - Elsevier
Lung cancer is one of the most prevalent tumors with rapid progression and poor prognosis,
which badly affects human physical and mental health. Although traditional anti-cancer …

Zein-yeast carboxymethyl glucan particles formed by anti-solvent precipitation for encapsulating resveratrol

X Bao, S Rong, Q Fu, H Liu, Y Han, F Liu, Z Ye… - International Journal of …, 2023 - Elsevier
In the work, zein-yeast carboxymethyl glucan (ZY) particles were fabricated by a novel
ultrasonic assisted anti-solvent precipitation (ASP) method, which was a good delivery …

Surface-modified biobased polymeric nanoparticles for dual delivery of doxorubicin and gefitinib in glioma cell lines

M Farheen, MH Akhter, H Chitme, M Suliman… - ACS …, 2023 - ACS Publications
Glioma is a malignant form of brain cancer that is challenging to treat due to the progressive
growth of glial cells. To target overexpressed folate receptors in glioma brain tumors, we …

Harnessing folate-functionalized nasal delivery of dox–erlo-loaded biopolymeric nanoparticles in cancer treatment: development, optimization, characterization, and …

M Farheen, MH Akhter, H Chitme, MS Akhter… - Pharmaceuticals, 2023 - mdpi.com
The aim of the present study is to develop Doxorubicin–Erlotinib nanoparticles (Dox–Erlo
NPs) and folate-armored Dox–Erlo-NP conjugates for targeting glioma cancer. Glioma is …