Quinoline and Quinazoline Alkaloids against COVID‐19: An In Silico Multitarget Approach
EMOA Ismail, SW Shantier, MS Mohammed… - Journal of …, 2021 - Wiley Online Library
The recent outbreak of the highly contagious coronavirus disease 2019 (COVID‐19) caused
by the novel coronavirus SARS‐CoV‐2 has created a global health crisis with …
by the novel coronavirus SARS‐CoV‐2 has created a global health crisis with …
Natural enantiomers: Occurrence, biogenesis and biological properties
The knowledge that natural products (NPs) are potent and selective modulators of important
biomacromolecules (eg, DNA and proteins) has inspired some of the world's most …
biomacromolecules (eg, DNA and proteins) has inspired some of the world's most …
[HTML][HTML] Anticancer activities of tetra-, penta-, and hexacyclic phenothiazines modified with quinoline moiety.
M Jeleń, B Morak-Młodawska, R Korlacki - Journal of Molecular Structure, 2023 - Elsevier
The quinoline molecule is a chemical motif showing a highly promising pharmacological
potential. Its numerous derivatives introduced into medicine revolutionized in the treatment …
potential. Its numerous derivatives introduced into medicine revolutionized in the treatment …
Advancement of corrosion inhibitor system through N-heterocyclic compounds: a review
Organic compounds containing heteroatoms have been comprehended to exhibit a
remarkable tendency towards corrosion mitigation. This corrosion mitigating tendency is …
remarkable tendency towards corrosion mitigation. This corrosion mitigating tendency is …
Visible-light photoredox catalyzed double C–H functionalization: radical cascade cyclization of ethers with benzimidazole-based cyanamides
S Jiang, XJ Tian, SY Feng, JS Li, ZW Li, CH Lu… - Organic …, 2021 - ACS Publications
A visible-light photoredox catalyzed radical cascade cyclization of simple ethers with
cyanamides is developed at room temperature. This strategy involves sequential inert Csp3 …
cyanamides is developed at room temperature. This strategy involves sequential inert Csp3 …
Unexpected assembly machinery for 4(3H)-quinazolinone scaffold synthesis
XW Chen, L Rao, JL Chen, Y Zou - Nature Communications, 2022 - nature.com
Abstract 4 (3 H)-quinazolinone is the core scaffold in more than 200 natural alkaloids and
numerous drugs. Many chemosynthetic methodologies have been developed to generate it; …
numerous drugs. Many chemosynthetic methodologies have been developed to generate it; …
Traditional uses, phytochemistry, pharmacology, toxicology and formulation aspects of Glycosmis species: a systematic review
PK Teja, P Patel, D Bhavsar, C Bindusri, K Jadhav… - Phytochemistry, 2021 - Elsevier
The present article is a systematic and constructive review of the traditional medicinal uses,
chemistry, pharmacology, toxicology, and formulation aspects of Glycosmis species. The …
chemistry, pharmacology, toxicology, and formulation aspects of Glycosmis species. The …
Natural 3,4-dihydro-2(1H)-quinolinones- Part I: plant sources
S Khadem, RJ Marles - Natural Product Research, 2024 - Taylor & Francis
While natural products have undoubtedly played a pivotal role in drug discovery, their
potential as lead compounds has been hindered by challenges such as limited accessibility …
potential as lead compounds has been hindered by challenges such as limited accessibility …
Quinoline‐based thiazolidinone derivatives as potent cytotoxic and apoptosis‐inducing agents through EGFR inhibition
Quinoline‐based thiazolidinone heterocycles exhibited potent activity in the field of cancer
therapy. Hence, ten quinoline‐based thiazolidinone derivatives were evaluated for their …
therapy. Hence, ten quinoline‐based thiazolidinone derivatives were evaluated for their …
Iron-catalysed quinoline synthesis via acceptorless dehydrogenative coupling
K Yu, Q Chen, W Liu - Organic Chemistry Frontiers, 2022 - pubs.rsc.org
An atom-economical and straightforward methodology for the synthesis of quinolines from α-
2-aminoaryl alcohols and secondary alcohols is presented. Using the Earth-abundant and …
2-aminoaryl alcohols and secondary alcohols is presented. Using the Earth-abundant and …