Quinoline and Quinazoline Alkaloids against COVID‐19: An In Silico Multitarget Approach

EMOA Ismail, SW Shantier, MS Mohammed… - Journal of …, 2021 - Wiley Online Library
The recent outbreak of the highly contagious coronavirus disease 2019 (COVID‐19) caused
by the novel coronavirus SARS‐CoV‐2 has created a global health crisis with …

Natural enantiomers: Occurrence, biogenesis and biological properties

JH Yu, ZP Yu, RJ Capon, H Zhang - Molecules, 2022 - mdpi.com
The knowledge that natural products (NPs) are potent and selective modulators of important
biomacromolecules (eg, DNA and proteins) has inspired some of the world's most …

[HTML][HTML] Anticancer activities of tetra-, penta-, and hexacyclic phenothiazines modified with quinoline moiety.

M Jeleń, B Morak-Młodawska, R Korlacki - Journal of Molecular Structure, 2023 - Elsevier
The quinoline molecule is a chemical motif showing a highly promising pharmacological
potential. Its numerous derivatives introduced into medicine revolutionized in the treatment …

Advancement of corrosion inhibitor system through N-heterocyclic compounds: a review

Sheetal, R Batra, AK Singh, M Singh… - Corrosion …, 2023 - Taylor & Francis
Organic compounds containing heteroatoms have been comprehended to exhibit a
remarkable tendency towards corrosion mitigation. This corrosion mitigating tendency is …

Visible-light photoredox catalyzed double C–H functionalization: radical cascade cyclization of ethers with benzimidazole-based cyanamides

S Jiang, XJ Tian, SY Feng, JS Li, ZW Li, CH Lu… - Organic …, 2021 - ACS Publications
A visible-light photoredox catalyzed radical cascade cyclization of simple ethers with
cyanamides is developed at room temperature. This strategy involves sequential inert Csp3 …

Unexpected assembly machinery for 4(3H)-quinazolinone scaffold synthesis

XW Chen, L Rao, JL Chen, Y Zou - Nature Communications, 2022 - nature.com
Abstract 4 (3 H)-quinazolinone is the core scaffold in more than 200 natural alkaloids and
numerous drugs. Many chemosynthetic methodologies have been developed to generate it; …

Traditional uses, phytochemistry, pharmacology, toxicology and formulation aspects of Glycosmis species: a systematic review

PK Teja, P Patel, D Bhavsar, C Bindusri, K Jadhav… - Phytochemistry, 2021 - Elsevier
The present article is a systematic and constructive review of the traditional medicinal uses,
chemistry, pharmacology, toxicology, and formulation aspects of Glycosmis species. The …

Natural 3,4-dihydro-2(1H)-quinolinones- Part I: plant sources

S Khadem, RJ Marles - Natural Product Research, 2024 - Taylor & Francis
While natural products have undoubtedly played a pivotal role in drug discovery, their
potential as lead compounds has been hindered by challenges such as limited accessibility …

Quinoline‐based thiazolidinone derivatives as potent cytotoxic and apoptosis‐inducing agents through EGFR inhibition

MS Nafie, SM Kishk, S Mahgoub… - Chemical Biology & …, 2022 - Wiley Online Library
Quinoline‐based thiazolidinone heterocycles exhibited potent activity in the field of cancer
therapy. Hence, ten quinoline‐based thiazolidinone derivatives were evaluated for their …

Iron-catalysed quinoline synthesis via acceptorless dehydrogenative coupling

K Yu, Q Chen, W Liu - Organic Chemistry Frontiers, 2022 - pubs.rsc.org
An atom-economical and straightforward methodology for the synthesis of quinolines from α-
2-aminoaryl alcohols and secondary alcohols is presented. Using the Earth-abundant and …