While natural products have undoubtedly played a pivotal role in drug discovery, their
potential as lead compounds has been hindered by challenges such as limited accessibility …

A visible-light photoredox catalyzed radical cascade cyclization of simple ethers with
cyanamides is developed at room temperature. This strategy involves sequential inert Csp3 …

Abstract 4 (3 H)-quinazolinone is the core scaffold in more than 200 natural alkaloids and
numerous drugs. Many chemosynthetic methodologies have been developed to generate it; …

Background: Chagas disease (American Trypanosomiasis) is classified by the World Health
Organization (WHO) as one of the seventeen neglected tropical diseases (NTD), affecting …

Quinoline‐based thiazolidinone heterocycles exhibited potent activity in the field of cancer
therapy. Hence, ten quinoline‐based thiazolidinone derivatives were evaluated for their …

An atom-economical and straightforward methodology for the synthesis of quinolines from α-
2-aminoaryl alcohols and secondary alcohols is presented. Using the Earth-abundant and …

Plant bacterial illnesses are common and cause dramatic damage to agricultural goods all
over the world, yet there are few efficient bactericides to alleviate them at present. To …

Crop diseases caused by fungi threaten food security and exacerbate the food crisis.
Inspired by the application of fungicide candidates from natural products in agrochemical …

Coumarins, widely abundant natural heterocyclic compounds, are extensively employed in
creating various biologically and pharmacologically potent substances. The hybridization of …

A new series of quinoline derivatives 5–12 were efficiently synthesized via one-pot
multicomponent reaction (MCR) of resorcinol, aromatic aldehydes, β-ketoesters, and …