Natural 3,4-dihydro-2(1h)-quinolinones- Part II: animal, bacterial, and fungal sources
S Khadem, RJ Marles - Natural Product Research, 2024 - Taylor & Francis
While natural products have undoubtedly played a pivotal role in drug discovery, their
potential as lead compounds has been hindered by challenges such as limited accessibility …
potential as lead compounds has been hindered by challenges such as limited accessibility …
[HTML][HTML] Coumarin-1, 2, 3-triazole hybrids as leading-edge anticancer agents
KN Mishra, HC Upadhyay - Frontiers in Drug Discovery, 2022 - frontiersin.org
Cancer is one of the most feared and dreaded diseases across the world. In clinical practice,
a variety of anticancer agents of natural, semi-synthetic and synthetic origin exist, but they …
a variety of anticancer agents of natural, semi-synthetic and synthetic origin exist, but they …
Visible-Light-Mediated Oxidative Cyclization of 2-Aminobenzyl Alcohols and Secondary Alcohols Enabled by an Organic Photocatalyst
J Xu, N Pan, J Chen, J Zhao - The Journal of Organic Chemistry, 2021 - ACS Publications
This paper describes a visible-light-mediated oxidative cyclization of 2-aminobenzyl
alcohols and secondary alcohols to produce quinolines at room temperature. This …
alcohols and secondary alcohols to produce quinolines at room temperature. This …
Synthesis and preliminary structure-activity relationship study of 3-methylquinazolinone derivatives as EGFR inhibitors with enhanced antiproliferative activities …
Y Zhang, Q Wang, L Li, Y Le, L Liu, J Yang… - Journal of Enzyme …, 2021 - Taylor & Francis
In this paper, a set of 3-methylquniazolinone derivatives were designed, synthesised, and
studied the preliminary structure-activity relationship for antiproliferative activities. All target …
studied the preliminary structure-activity relationship for antiproliferative activities. All target …
[HTML][HTML] Chemical Composition of Combretum erythrophyllum Leaf and Stem Bark Extracts
Combretaceae is a large Angiosperm family that is highly sought after because of its
pronounced medicinal value. Combretum is recognized as the largest genus, prevalent in …
pronounced medicinal value. Combretum is recognized as the largest genus, prevalent in …
Azole-based antibacterial agents: A review on multistep synthesis strategies and biology
This article reviews current multistep synthesis strategies of azole-based antibacterial
agents. In recent years, extensive use of chemical agents in treating different diseases …
agents. In recent years, extensive use of chemical agents in treating different diseases …
Biology of quinoline and quinazoline alkaloids
XF Shang, SL Morris-Natschke, YQ Liu, XH Li… - The Alkaloids: Chemistry …, 2022 - Elsevier
Quinoline and quinazoline alkaloids, two important classes of N-based heterocyclic
compounds, have attracted scientific and popular interest worldwide since the 19th century …
compounds, have attracted scientific and popular interest worldwide since the 19th century …
Synthesis, biological evaluation and in silico computational studies of 7-chloro-4-(1 H-1, 2, 3-triazol-1-yl) quinoline derivatives: Search for new controlling agents …
DN Rosado-Solano, MA Barón-Rodríguez… - Journal of agricultural …, 2019 - ACS Publications
The insecticidal and antifeedant activities of five 7-chloro-4-(1 H-1, 2, 3-triazol-1-yl) quinoline
derivatives were evaluated against the maize armyworm, Spodoptera frugiperda (JE Smith) …
derivatives were evaluated against the maize armyworm, Spodoptera frugiperda (JE Smith) …
In Situ Sprayed Biotherapeutic Gel Containing Stable Microbial Communities for Efficient Anti‐Infection Treatment
Systematic administration of antibiotics to treat infections often leads to the rapid evolution
and spread of multidrug‐resistant bacteria. Here, an in situ‐formed biotherapeutic gel that …
and spread of multidrug‐resistant bacteria. Here, an in situ‐formed biotherapeutic gel that …
Continuous Flow Synthesis of Quinolines via a Scalable Tandem Photoisomerization‐Cyclization Process
M Di Filippo, M Baumann - European Journal of Organic …, 2020 - Wiley Online Library
A continuous photochemical process is presented that renders a series of quinoline
products via an alkene isomerization and cyclocondensation cascade. It is demonstrated …
products via an alkene isomerization and cyclocondensation cascade. It is demonstrated …