Exploring the Dynamical Nature of Intermolecular Hydrogen Bonds in Benzamide, Quinoline and Benzoic Acid Derivatives

K Wojtkowiak, A Jezierska - Molecules, 2022 - mdpi.com
The hydrogen bonds properties of 2, 6-difluorobenzamide, 5-hydroxyquinoline and 4-
hydroxybenzoic acid were investigated by Car–Parrinello and path integral molecular …

Design, synthesis and biological evaluation of tanshinone IIA-based analogues: potent inhibitors of microtubule formation and angiogenesis

H Huang, Y Yao, G Hou, C Zhao, J Qin, Y Zhang… - European Journal of …, 2021 - Elsevier
We report the structural optimization of tanshinone IIA, a natural product which possesses
anti-tumor properties but low water-solubility, weak antiproliferative activity and poor PK …

[PDF][PDF] Performance of organic molecules as corrosion inhibitors for CS: a comprehensive review

M Karaoui, AM Zarrouk, R Hsissou… - Analytical and …, 2022 - researchgate.net
Organic molecules have occupied an important place by researchers and chemists in the
field of corrosion inhibition of metals in various corrosive media such as HCl. Owing to the …

Secondary Amine‐Mediated Domino Reaction for the Synthesis of Substituted Quinolines from Dicyanoalkenes and Enynals

Y Hayashi, X Han, N Mori - Chemistry–A European Journal, 2023 - Wiley Online Library
Substituted quinolines, tricyclic and tetracyclic molecules with a quinoline moiety are
synthesized by a domino reaction from dicyanoalkenes and 3‐aryl‐pent‐2‐en‐4‐ynals in …

[HTML][HTML] Kokusaginine attenuates renal fibrosis by inhibiting the PI3K/AKT signaling pathway

Y Wang, Y Han, K Shang, J Xiao, L Tao, Z Peng… - Biomedicine & …, 2024 - Elsevier
Kokusaginine is an active ingredient alkaloid that has been isolated and extracted from Ruta
graveolens L. Some researches have indicated that alkaloids possess anti-inflammatory and …

Quinoline Derivatives in Discovery and Development of Pesticides

Q Cai, H Song, Y Zhang, Z Zhu, J Zhang… - Journal of Agricultural …, 2024 - ACS Publications
Finding highly active molecular scaffold structures is always the key research content of new
pesticide discovery. In the research and development of new pesticides, the discovery of …

Regio- and Stereoselective Intermolecular 1,2-Difunctionalization of Terminal Alkynes: An Approach to Access (Z)-β-Amidovinylsulfones

R Kumar, D Bhadoria, R Kant… - The Journal of Organic …, 2024 - ACS Publications
We have developed the first I2/base-catalyzed regio-and stereoselective intermolecular β-
amidosulfonylation of terminal alkynes using sodium sulfinates and quinoxalinone …

[HTML][HTML] Cuspareine as alkaloid against COVID-19 designed with ionic liquids: DFT and docking molecular approaches

NM Mahani, F Mostaghni, H Shafiekhani - Journal of Photochemistry and …, 2022 - Elsevier
Cuspareine as an antiviral alkaloid can be used in the treatment of COVID-19. In this study,
we introduced the ionic liquids (ILs) concluded cuspareinium as a cation with CH 3 COO …

VOC fingerprints: Metabolomic signatures of biothreat agents with and without antibiotic resistance

A Dailey, J Saha, F Zaidi, H Abdirahman… - Scientific Reports, 2020 - nature.com
Category A and B biothreat agents are deemed to be of great concern by the US Centers for
Disease Control and Prevention (CDC) and include the bacteria Francisella tularensis …

Synthesis and evaluation of the anti-inflammatory activity of novel 8-quinolinesulfonamide derivatives as TLR4/MD-2 inhibitors with efficacy in adjuvant-induced …

T Liu, S Xing, J Du, M Wang, J Han, Z Li - Bioorganic Chemistry, 2021 - Elsevier
In this study, a series of 8-quinolinesulfonamide derivatives was synthesized, and their anti-
inflammatory activity was evaluated. Among them, compound 3l was found to be the best …