The regulation of protein translation and its implications for cancer
P Song, F Yang, H Jin, X Wang - Signal transduction and targeted …, 2021 - nature.com
In addition to the deregulation of gene transcriptions and post-translational protein
modifications, the aberrant translation from mRNAs to proteins plays an important role in the …
modifications, the aberrant translation from mRNAs to proteins plays an important role in the …
Emerging roles of circular RNAs in gastric cancer metastasis and drug resistance
X Wang, J Zhang, G Cao, J Hua, G Shan… - Journal of Experimental & …, 2022 - Springer
Gastric cancer (GC) is an aggressive malignancy with a high mortality rate and poor
prognosis, primarily caused by metastatic lesions. Improved understanding of GC metastasis …
prognosis, primarily caused by metastatic lesions. Improved understanding of GC metastasis …
The FUS/circEZH2/KLF5/feedback loop contributes to CXCR4-induced liver metastasis of breast cancer by enhancing epithelial-mesenchymal transition
P Liu, Z Wang, X Ou, P Wu, Y Zhang, S Wu, X Xiao… - Molecular cancer, 2022 - Springer
Background Metastasis of breast cancer have caused the majority of cancer-related death
worldwide. The circRNAs are associated with tumorigenesis and metastasis in breast cancer …
worldwide. The circRNAs are associated with tumorigenesis and metastasis in breast cancer …
Cancer cell-derived exosomal circUHRF1 induces natural killer cell exhaustion and may cause resistance to anti-PD1 therapy in hepatocellular carcinoma
PF Zhang, C Gao, XY Huang, JC Lu, XJ Guo, GM Shi… - Molecular cancer, 2020 - Springer
Objective Natural killer (NK) cells play a critical role in the innate antitumor immune
response. Recently, NK cell dysfunction has been verified in various malignant tumors …
response. Recently, NK cell dysfunction has been verified in various malignant tumors …
The circRNA circSEPT9 mediated by E2F1 and EIF4A3 facilitates the carcinogenesis and development of triple-negative breast cancer
X Zheng, M Huang, L Xing, R Yang, X Wang, R Jiang… - Molecular cancer, 2020 - Springer
Background Increasing studies have shown that circRNA is closely related to the
carcinogenesis and development of many cancers. However, biological functions and the …
carcinogenesis and development of many cancers. However, biological functions and the …
The circular RNA circHMGB2 drives immunosuppression and anti-PD-1 resistance in lung adenocarcinomas and squamous cell carcinomas via the miR-181a-5p …
LX Zhang, J Gao, X Long, PF Zhang, X Yang, SQ Zhu… - Molecular Cancer, 2022 - Springer
Background Previous studies have confirmed the oncogenic role of HMGB2 in various
cancers, but the biological functions of HMGB2-derived circRNAs remain unknown. Thus …
cancers, but the biological functions of HMGB2-derived circRNAs remain unknown. Thus …
The circROBO1/KLF5/FUS feedback loop regulates the liver metastasis of breast cancer by inhibiting the selective autophagy of afadin
Background Metastasis causes the majority of cancer-related deaths worldwide. Increasing
studies have revealed that circRNAs are associated with the carcinogenesis and metastasis …
studies have revealed that circRNAs are associated with the carcinogenesis and metastasis …
CircSEMA4B inhibits the progression of breast cancer by encoding a novel protein SEMA4B-211aa and regulating AKT phosphorylation
X Wang, W Jian, Q Luo, L Fang - Cell death & disease, 2022 - nature.com
Abstract PI3K/AKT signaling pathway plays an important role in regulating the
tumorigenesis, recurrence, and metastasis of breast cancer (BC). In this study, we …
tumorigenesis, recurrence, and metastasis of breast cancer (BC). In this study, we …
Exosomal circGSE1 promotes immune escape of hepatocellular carcinoma by inducing the expansion of regulatory T cells
M Huang, X Huang, N Huang - Cancer Science, 2022 - Wiley Online Library
Studies have shown exosomal circRNAs can regulate the immune escape of tumors by
carrying cancer‐derived molecules. Regulatory T cells (Tregs) participate in the process of …
carrying cancer‐derived molecules. Regulatory T cells (Tregs) participate in the process of …
RNMFLP: predicting circRNA–disease associations based on robust nonnegative matrix factorization and label propagation
Circular RNAs (circRNAs) are a class of structurally stable endogenous noncoding RNA
molecules. Increasing studies indicate that circRNAs play vital roles in human diseases …
molecules. Increasing studies indicate that circRNAs play vital roles in human diseases …