Multimodal analgesia for acute postoperative and trauma-related pain

RC Polomano, M Fillman, NA Giordano… - AJN The American …, 2017 - journals.lww.com
Multimodal analgesia, which combines analgesic drugs from different classes and employs
analgesic techniques that target different mechanisms of pain, is recommended in the …

Do polyunsaturated fatty acids protect against bone loss in our aging and osteoporotic population?

K Martyniak, F Wei, A Ballesteros, T Meckmongkol… - Bone, 2021 - Elsevier
Age-related bone loss is inevitable in both men and women and there will soon be more
people of extreme old age than ever before. Osteoporosis is a common chronic disease and …

Photobiomodulation therapy (PBMT) on acute pain and inflammation in patients who underwent total hip arthroplasty—a randomized, triple-blind, placebo-controlled …

LG Langella, HL Casalechi, SS Tomazoni… - Lasers in medical …, 2018 - Springer
When conservative treatments fail, hip osteoarthritis (OA), a chronic degenerative disease
characterized by cartilage wear, progressive joint deformity, and loss of function, can result …

[HTML][HTML] 1, 25-Dihydroxyvitamin D suppresses M1 macrophages and promotes M2 differentiation at bone injury sites

S Wasnik, CH Rundle, DJ Baylink, MS Yazdi… - JCI insight, 2018 - ncbi.nlm.nih.gov
An indispensable role of macrophages in bone repair has been well recognized. Previous
data have demonstrated the copresence of M1 macrophages and mesenchymal stem cells …

Mg2+‐mediated autophagy‐dependent polarization of macrophages mediates the osteogenesis of bone marrow stromal stem cells by interfering with macrophage …

Y Zhu, S Zhao, L Cheng, Z Lin, M Zeng… - Journal of …, 2022 - Wiley Online Library
Abstract Magnesium ion (Mg2+) has received increased attention due to the roles it plays in
promoting osteogenesis and preventing inflammation. This study was designed to …

The effect of opioids, alcohol, and nonsteroidal anti-inflammatory drugs on fracture union

CJ Richards, KW Graf, RP Mashru - Orthopedic Clinics, 2017 - orthopedic.theclinics.com
Fracture union is a complex process that is intimately related to the biologic and mechanical
environments at the fracture site. Improper fracture fixation ranging from undersized …

SIRT1 was involved in TNF-α-promoted osteogenic differentiation of human DPSCs through Wnt/β-catenin signal

G Feng, K Zheng, D Song, K Xu, D Huang… - In Vitro Cellular & …, 2016 - Springer
Dental pulp stem cells (DPSCs), as one type of mesenchymal stem cells (MSCs), have the
capability of self-renewal and differentiating along the various directions, including …

Self-reported marijuana use is associated with increased use of prescription opioids following traumatic musculoskeletal injury

AR Bhashyam, M Heng, MB Harris, MS Vrahas… - JBJS, 2018 - journals.lww.com
Background: Cannabinoids are among the psychoactive substances considered as
alternatives to opioids for the alleviation of acute pain. We examined whether self-reported …

[HTML][HTML] Platelet-rich plasma injection in burn scar areas alleviates neuropathic scar pain

SH Huang, SH Wu, SS Lee, YN Lin… - … Journal of Medical …, 2018 - ncbi.nlm.nih.gov
Objective: No effective treatments have yet been developed for burn-induced neuropathic
pain. Platelet-rich plasma (PRP) has been reported to ameliorate various types of …

Socioeconomic status affects postoperative time to union in pediatric patients with a surgically treated fracture

DM Heath, AN Ghali, DA Momtaz, S Nagel… - JBJS Open …, 2023 - journals.lww.com
Background: Fractures account for 10% to 25% of all pediatric injuries, and surgical
treatment is common. In such cases, postoperative healing can be affected by a number of …