Skeletal muscle regenerates through the activation of resident stem cells. Termed satellite
cells, these normally quiescent cells are induced to proliferate by wound-derived signals …

Memory formation, guided by microbial ligands, has been reported for innate immune cells.
Epigenetic imprinting plays an important role herein, involving histone modification after …

De novo beige adipocyte biogenesis involves the proliferation of progenitor cells in white
adipose tissue (WAT); however, what regulates this process remains unclear. Here, we …

Infections caused by Cryptococcus neoformans and Cryptococcus gattii remain a challenge
to our healthcare systems as they are still difficult to treat. In order to improve treatment …

Macrophage phenotypes are poorly characterized in disease systems in vivo. Appropriate
macrophage activation requires complex coordination of local microenvironmental cues and …

Background TNF-related apoptosis-inducing ligand (TRAIL) is a member of the TNF
superfamily that can either induce cell death or activate survival pathways after binding to …

A primary virulence-associated trait of the opportunistic fungal pathogen Cryptococcus
neoformans is the production of melanin pigments that are deposited into the cell wall and …

Invasive aspergillosis is a common opportunistic infection, causing> 50% mortality in
infected immunocompromised patients. The specific molecular mechanisms of the innate …

Neutrophilic inflammation with prolonged neutrophil survival is common to many
inflammatory conditions, including chronic obstructive pulmonary disease (COPD). There …

To study the dynamics of infection processes, it is common to manually enumerate imaging‐
based infection assays. However, manual counting of events from imaging data is biased …