Targeting non-coding RNAs to overcome cancer therapy resistance
BQ Chen, MP Dragomir, C Yang, Q Li, D Horst… - Signal transduction and …, 2022 - nature.com
It is now well known that non-coding RNAs (ncRNAs), rather than protein-coding transcripts,
are the preponderant RNA transcripts. NcRNAs, particularly microRNAs (miRNAs), long non …
are the preponderant RNA transcripts. NcRNAs, particularly microRNAs (miRNAs), long non …
Genetic biomarkers and their clinical implications in B-cell acute lymphoblastic leukemia in children
M Lejman, A Chałupnik, Z Chilimoniuk… - International journal of …, 2022 - mdpi.com
Acute lymphoblastic leukemia (ALL) is a heterogeneous group of hematologic malignancies
characterized by abnormal proliferation of immature lymphoid cells. It is the most commonly …
characterized by abnormal proliferation of immature lymphoid cells. It is the most commonly …
The effect of apigenin and chemotherapy combination treatments on apoptosis-related genes and proteins in acute leukaemia cell lines
Apigenin is a dietary polyphenol found abundantly in fruit and vegetables, which sensitizes
leukaemia cells to topoisomerase inhibitor agents (eg, etoposide), and alkylating agents (eg …
leukaemia cells to topoisomerase inhibitor agents (eg, etoposide), and alkylating agents (eg …
Evaluation and application of drug resistance by biomarkers in the clinical treatment of liver cancer
PS Huang, LY Wang, YW Wang, MM Tsai, TK Lin… - Cells, 2023 - mdpi.com
Liver cancer is one of the most lethal cancers in the world, mainly owing to the lack of
effective means for early monitoring and treatment. Accordingly, there is considerable …
effective means for early monitoring and treatment. Accordingly, there is considerable …
The PP2A subunit PR130 is a key regulator of cell development and oncogenic transformation
M Dzulko, M Pons, A Henke, G Schneider… - … et Biophysica Acta (BBA …, 2020 - Elsevier
Abstract Protein phosphatase 2A (PP2A) is a major serine/threonine phosphatase. This
enzyme is involved in a plethora of cellular processes, including apoptosis, autophagy, cell …
enzyme is involved in a plethora of cellular processes, including apoptosis, autophagy, cell …
[HTML][HTML] Amelioration of human acute lymphoblastic leukemia (ALL) cells by ZnO-TiO2-Chitosan-Amygdalin nanocomposites
AY Elderdery, B Alzahrani, F Alanazi… - Arabian Journal of …, 2022 - Elsevier
The present study aims to study the cytotoxicity of ZnO-TiO 2-Chitosan-Amygdalin
nanocomposites (ZnO-TiO 2-Chitosan-Amygdalin) on T lymphoblast cancer cells (MOLT-4) …
nanocomposites (ZnO-TiO 2-Chitosan-Amygdalin) on T lymphoblast cancer cells (MOLT-4) …
Non-coding RNA signatures of B-cell acute lymphoblastic leukemia
PD Rodriguez, H Paculova, S Kogut, J Heath… - International Journal of …, 2021 - mdpi.com
Non-coding RNAs (ncRNAs) comprise a diverse class of non-protein coding transcripts that
regulate critical cellular processes associated with cancer. Advances in RNA-sequencing …
regulate critical cellular processes associated with cancer. Advances in RNA-sequencing …
Effective and Efficient Delivery of Genome-Based Testing-What Conditions Are Necessary for Health System Readiness?
Health systems internationally must prepare for a future of genetic/genomic testing to inform
healthcare decision-making while creating research opportunities. High functioning testing …
healthcare decision-making while creating research opportunities. High functioning testing …
Puzzling out iron complications in cancer drug resistance
M Abedi, S Rahgozar - Critical Reviews in Oncology/Hematology, 2022 - Elsevier
Iron metabolism are frequently disrupted in cancer. Patients with cancer are prone to anemia
and receive transfusions frequently; the condition which results in iron overload, contributing …
and receive transfusions frequently; the condition which results in iron overload, contributing …