1, 1, 1, 3, 3, 3-Hexafluoroisopropanol (HFIP) is a polar, strongly hydrogen bond-donating
solvent that has found numerous uses in organic synthesis due to its ability to stabilize ionic …

Transition-metal-catalyzed reactions have been studied since the very beginning of the past
century and represent a great success in organic chemistry, along with the birth and growth …

Transition Metal-Mediated Synthesis of Monocyclic Aromatic Heterocycles | Chemical Reviews
ACS ACS Publications C&EN CAS Find my institution Log In Chemical Reviews ACS …

The C–N cross-coupling chemistry intensely developed since the late 1990s has supplied
synthesists with an overwhelming number of methods to effectively combine carbon and …

Significant progress has been accomplished in directed C–H functionalization through the
use of earth-abundant and inexpensive first-row transition metals. Among these base …

Transition metal-catalyzed C–H amination at positions adjacent to double bonds and
carbonyl groups is discussed in this critical review. While the focus will center on the recent …

It's all in the solvent: An enantioselective variant of an aza-Wacker-type cyclization that gives
isoindolinones containing tetrasubstituted carbon centers α to the nitrogen atom has been …

Palladium-Catalyzed Intramolecular C(sp2)–H Amidination by Isonitrile Insertion Provides
Direct Access to 4-Aminoquinazolines from N-Arylamidines | Organic Letters ACS ACS …

Heterocyclic compounds are ubiquitous in natural products, pharmaceuticals, and
agrochemicals. Therefore, the design of novel protocols to construct heterocycles more …

We have developed an asymmetric aza-Wacker-type cyclization of N-Ts hydrazine-tethered
tetrasubstituted olefins, affording optically active pyrazolines bearing chiral tetrasubstituted …