Lipid metabolic reprogramming is an emerging hallmark of cancer. In order to sustain
uncontrolled proliferation and survive in unfavorable environments that lack oxygen and …

The innate immune pathway is receiving increasing attention in cancer therapy. This
pathway is ubiquitous across various cell types, not only in innate immune cells but also in …

Lipids, as one of the three primary energy sources, provide energy for all cellular life
activities. Lipids are also known to be involved in the formation of cell membranes and play …

For decades, great strides have been made in the field of immunometabolism. A plethora of
evidence ranging from basic mechanisms to clinical transformation has gradually embarked …

The tumor microenvironment (TME) in pancreatic ductal adenocarcinoma (PDAC) involves a
significant accumulation of cancer-associated fibroblasts (CAFs) as part of the host response …

Background Increasing evidence suggests a vital role of the pre-metastatic niche in the
formation of distant metastasis of many cancers. However, how the pre-metastatic niche is …

Over the past decade, extracellular vesicles and particles (EVPs) have emerged as critical
mediators of intercellular communication, participating in numerous physiological and …

Lipid metabolism in cancer cells has garnered increasing attention in recent decades.
Cancer cells thrive in hypoxic conditions, nutrient deficiency, and oxidative stress and …

Breast cancer (BC) is one of the most commonly diagnosed cancers and the leading cause
of cancer-related deaths in women worldwide. Metastasis is a major contributor to high …

As an important mediator of information transfer between cells, exosomes play a unique role
in regulating tumor growth, supporting vascular proliferation, tumor invasion, and metastasis …