Serotonin (5-HT) neuron and neurotransmitter loss in normal aging and neuropsychiatric
diseases of late life may contribute to behavioral changes commonly observed in the elderly …

Over the last 10 years there has been important progress towards understanding how
neurotransmitters regulate dopaminergic output. Reasonable estimates can be made of the …

Since their discovery in the mammalian brain, it has been apparent that serotonin (5-HT)
and dopamine (DA) interactions play a key role in normal and abnormal behavior …

Extensive evidence indicates that disruption of cholinergic funtion is characteristic of aging
and Alzheimer's disease (AD), and experimental manipulation of the cholinergic system in …

Cholinergic systems have been linked to cognitive processes such as attention, learning
and mnemonic function. However, other neurotransmitter systems, such as the serotonergic …

Accumulating evidence suggests that serotonin may modulate cholinergic function in
several regions of the mammalian brain and that these serotonergic/cholinergic interactions …

Several recent studies have emphasized a crucial role for the interactions between
serotonergic and dopaminergic systems in movement control and the pathophysiology of …

Neuropathological and neuroimaging studies have consistently demonstrated degeneration
of monoamine systems, especially the serotonin system, in normal aging and Alzheimer's …

Using microdialysis, changes in extraneuronal levels of dopamine (DA), and the metabolites
of DA and serotonin (5-HT), were monitored concurrent with perfusion of 5-HT 1 agonists …

Pre-exposure of rats to systemic injections of d-amphetamine sulfate in the presence of
bilateral injections of Sch-23390 (0.5 or 1.0 μg/side) into the ventral tegmental area (VTA) …