Precipitous Release of Methyl-CpG Binding Protein 2 and Histone Deacetylase 1 from the Methylated Human Multidrug Resistance Gene (MDR1) on Activation
A El-Osta, P Kantharidis, JR Zalcberg… - Molecular and cellular …, 2002 - Taylor & Francis
Overexpression of the human multidrug resistance gene 1 (MDR1) is a negative prognostic
factor in leukemia. Despite intense efforts to characterize the gene at the molecular level …
factor in leukemia. Despite intense efforts to characterize the gene at the molecular level …
Contrasting patterns and cellular specificity of transcriptional regulation of the nuclear receptor nerve growth factor‐inducible B by haloperidol and clozapine in the rat …
G Beaudry, MC Langlois, I Weppe… - Journal of …, 2000 - Wiley Online Library
This study was designed to investigate the possible involvement of members of the nuclear
receptor family of transcription factors in the effects of antipsychotic drugs used in the …
receptor family of transcription factors in the effects of antipsychotic drugs used in the …
Quantitating mRNAs with relative and competitive RT-PCR
EA Prediger - Nuclease Methods and Protocols, 2001 - Springer
Reverse transcription coupled with the polymerase chain reaction (RT-PCR), permits
amplification of cellular RNA. Gene expression can be measured even when the message …
amplification of cellular RNA. Gene expression can be measured even when the message …
SOLUBLE INTERLEUKINE-2 RECPTOR ANDMDR1 GENE EXPRESSION LEVELS AS INFLAMMATORY BIOMARKERS FOR PREDICTION OF STEROID …
DM Youssef, RM Elbehidy, HS Abdelhalim, GE Amr - 2011 - sid.ir
Introduction. Upregulation of interleukin-2 may be involved, not only in the pathophysiology
of NEPHROTIC SYNDROME, but also in steroid resistance treatment, by increasing …
of NEPHROTIC SYNDROME, but also in steroid resistance treatment, by increasing …
Multiple drug‐resistant gene 1 in children with steroid‐sensitive nephrotic syndrome
S Funaki, S Takahashi, N Wada… - Pediatrics …, 2008 - Wiley Online Library
Background: A full dose of corticosteroid is required to induce complete remission (CR) in
steroid‐sensitive nephrotic syndrome (SSNS), unless it is possible to taper and discontinue …
steroid‐sensitive nephrotic syndrome (SSNS), unless it is possible to taper and discontinue …
Tumor-specific regulation of angiogenic growth factors and their receptors during recovery from cytotoxic therapy
AP Taylor, L Osorio, R Craig, JA Raleigh, Z Ying… - Clinical cancer …, 2002 - AACR
After cytotoxic treatment, up-regulation of vascular growth factors and theirreceptors may be
crucial for tumor relapse or progression. Todetermine how cytotoxic therapy …
crucial for tumor relapse or progression. Todetermine how cytotoxic therapy …
Impaired 2′, 3′-dideoxy-3′-thiacytidine accumulation in T-lymphoblastoid cells as a mechanism of acquired resistance independent of multidrug resistant protein 4 …
Cellular factors may contribute to the decreased efficacy of chemotherapy in HIV infection.
Indeed, prolonged treatment with nucleoside analogues, such as azidothymidine (AZT), 2 …
Indeed, prolonged treatment with nucleoside analogues, such as azidothymidine (AZT), 2 …
Profiling methyl-CpG specific determinants on transcriptionally silent chromatin
A El-Osta, EK Baker, AP Wolffe - Molecular biology reports, 2001 - Springer
Transcriptional activity is closely associated with DNA methylation and chromatin
remodelling. Evidence is emerging that a family of methylation specific (methyl-CpG binding …
remodelling. Evidence is emerging that a family of methylation specific (methyl-CpG binding …
Analysis of chromatin-immunopurified MeCP2-associated fragments
A El-Osta, AP Wolffe - Biochemical and biophysical research …, 2001 - Elsevier
As molecular biologists, we are continuing to unravel the interactions by which DNA binding
proteins mediate the expression of genes. The chromatin immunoprecipitation (ChIP) …
proteins mediate the expression of genes. The chromatin immunoprecipitation (ChIP) …
多药耐药基因在肾病综合征患儿外周血单个核细胞中的表达研究
朱智， 俞建， 徐虹， 曹琦， 黄文彦， 周利军， 王莹 - 临床儿科杂志, 2009 - cqvip.com
目的探讨肾病综合征(NS) 患儿外周血单个核细胞(PBMC) 中多药耐药基因(MDR1)
的表达与不同激素(GC) 效应患儿的关系. 方法收集2007 年5 月-2008 年2 月收治的原发特发性 …
的表达与不同激素(GC) 效应患儿的关系. 方法收集2007 年5 月-2008 年2 月收治的原发特发性 …